    <SEC-DOCUMENT>0001534969-22-000057-index.html : 20220422
    <SEC-HEADER>0001534969-22-000057.hdr.sgml : 20220422
    <ACCEPTANCE-DATETIME>20220422160346
    ACCESSION NUMBER:		0001534969-22-000057
    CONFORMED SUBMISSION TYPE:	DEF 14A
    PUBLIC DOCUMENT COUNT:		5
    CONFORMED PERIOD OF REPORT:	20220603
    FILED AS OF DATE:		20220422
    DATE AS OF CHANGE:		20220422

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			SERA PROGNOSTICS, INC.
    		CENTRAL INDEX KEY:			0001534969
    		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-MEDICAL LABORATORIES [8071]
    		IRS NUMBER:				261911522
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		DEF 14A
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-40606
    		FILM NUMBER:		22845461

    	BUSINESS ADDRESS:
    		STREET 1:		2749 E. PARLEYS WAY
    		STREET 2:		SUITE 200
    		CITY:			SALT LAKE CITY
    		STATE:			UT
    		ZIP:			84109
    		BUSINESS PHONE:		(801) 990-0520

    	MAIL ADDRESS:
    		STREET 1:		2749 E. PARLEYS WAY
    		STREET 2:		SUITE 200
    		CITY:			SALT LAKE CITY
    		STATE:			UT
    		ZIP:			84109
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>DEF 14A
    <SEQUENCE>1
    <FILENAME>a2022seraproxy.htm
    <DESCRIPTION>DEF 14A
    <TEXT>
    Document 1 - file: a2022seraproxy.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>2
    <FILENAME>logo.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 2 - file: logo.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>3
    <FILENAME>seraprognosticsinc_p69382x.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 3 - file: seraprognosticsinc_p69382x.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>4
    <FILENAME>seraprognosticsinc_p69382xa.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 4 - file: seraprognosticsinc_p69382xa.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>5
    <FILENAME>signature.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 5 - file: signature.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>