    <SEC-DOCUMENT>0000950170-25-057359-index.html : 20250423
    <SEC-HEADER>0000950170-25-057359.hdr.sgml : 20250423
    <ACCEPTANCE-DATETIME>20250423161042
    ACCESSION NUMBER:		0000950170-25-057359
    CONFORMED SUBMISSION TYPE:	DEF 14A
    PUBLIC DOCUMENT COUNT:		5
    CONFORMED PERIOD OF REPORT:	20250605
    FILED AS OF DATE:		20250423
    DATE AS OF CHANGE:		20250423

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			SERA PROGNOSTICS, INC.
    		CENTRAL INDEX KEY:			0001534969
    		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-MEDICAL LABORATORIES [8071]
    		ORGANIZATION NAME:           	08 Industrial Applications and Services
    		EIN:				261911522
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		DEF 14A
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-40606
    		FILM NUMBER:		25861563

    	BUSINESS ADDRESS:
    		STREET 1:		2749 E. PARLEYS WAY
    		STREET 2:		SUITE 200
    		CITY:			SALT LAKE CITY
    		STATE:			UT
    		ZIP:			84109
    		BUSINESS PHONE:		(801) 990-0520

    	MAIL ADDRESS:
    		STREET 1:		2749 E. PARLEYS WAY
    		STREET 2:		SUITE 200
    		CITY:			SALT LAKE CITY
    		STATE:			UT
    		ZIP:			84109
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>DEF 14A
    <SEQUENCE>1
    <FILENAME>sera-def14a-2025.htm
    <DESCRIPTION>DEF 14A
    <TEXT>
    Document 1 - file: sera-def14a-2025.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>2
    <FILENAME>img222552585_0.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 2 - file: img222552585_0.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>3
    <FILENAME>img222552585_1.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 3 - file: img222552585_1.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>4
    <FILENAME>img222552585_2.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 4 - file: img222552585_2.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>5
    <FILENAME>img222552585_3.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 5 - file: img222552585_3.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>