<SEC-DOCUMENT>0001961863-25-000001.txt : 20250110
<SEC-HEADER>0001961863-25-000001.hdr.sgml : 20250110
<ACCEPTANCE-DATETIME>20250110172829
ACCESSION NUMBER:		0001961863-25-000001
CONFORMED SUBMISSION TYPE:	144
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20250110
DATE AS OF CHANGE:		20250110

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			SERA PROGNOSTICS, INC.
		CENTRAL INDEX KEY:			0001534969
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-MEDICAL LABORATORIES [8071]
		ORGANIZATION NAME:           	08 Industrial Applications and Services
		IRS NUMBER:				261911522
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		144
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	001-40606
		FILM NUMBER:		25524047

	BUSINESS ADDRESS:	
		STREET 1:		2749 E. PARLEYS WAY
		STREET 2:		SUITE 200
		CITY:			SALT LAKE CITY
		STATE:			UT
		ZIP:			84109
		BUSINESS PHONE:		(801) 990-0520

	MAIL ADDRESS:	
		STREET 1:		2749 E. PARLEYS WAY
		STREET 2:		SUITE 200
		CITY:			SALT LAKE CITY
		STATE:			UT
		ZIP:			84109

REPORTING-OWNER:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			CATALYST HEALTH VENTURES LP
		CENTRAL INDEX KEY:			0001429051
		ORGANIZATION NAME:           	
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE

	FILING VALUES:
		FORM TYPE:		144

	BUSINESS ADDRESS:	
		STREET 1:		ONE GATEWAY CENTER
		STREET 2:		SUITE 312
		CITY:			NEWTON
		STATE:			MA
		ZIP:			02458
		BUSINESS PHONE:		617-964-3100

	MAIL ADDRESS:	
		STREET 1:		ONE GATEWAY CENTER
		STREET 2:		SUITE 312
		CITY:			NEWTON
		STATE:			MA
		ZIP:			02458
</SEC-HEADER>
<DOCUMENT>
<TYPE>144
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
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  <headerData>
    <submissionType>144</submissionType>
    <filerInfo>
      <filer>
        <filerCredentials>
          <cik>0001429051</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>


    </filerInfo>
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  <formData>
    <issuerInfo>
      <issuerCik>0001534969</issuerCik>
      <issuerName>SERA PROGNOSTICS, INC.</issuerName>
      <secFileNumber>001-40606</secFileNumber>
      <issuerAddress>
        <com:street1>2749 E. PARLEYS WAY</com:street1>
        <com:street2>SUITE 200</com:street2>
        <com:city>SALT LAKE CITY</com:city>
        <com:stateOrCountry>UT</com:stateOrCountry>
        <com:zipCode>84109</com:zipCode>
      </issuerAddress>
      <issuerContactPhone>(801) 990-0520</issuerContactPhone>
      <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>CATALYST HEALTH VENTURES LP</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
      <relationshipsToIssuer>
        <relationshipToIssuer>Shareholder</relationshipToIssuer>
      </relationshipsToIssuer>
    </issuerInfo>
    <securitiesInformation>
      <securitiesClassTitle>Class A</securitiesClassTitle>
      <brokerOrMarketmakerDetails>
        <name>Merrill Lynch, Pierce, Fenner &amp; Smith Incorporated</name>
        <address>
          <com:street1>555 California Street</com:street1>
          <com:street2>18th Floor</com:street2>
          <com:city>San Francisco</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>94104</com:zipCode>
        </address>
      </brokerOrMarketmakerDetails>
      <noOfUnitsSold>6793</noOfUnitsSold>
      <aggregateMarketValue>56517.76</aggregateMarketValue>
      <noOfUnitsOutstanding>32804741</noOfUnitsOutstanding>
      <approxSaleDate>01/10/2025</approxSaleDate>
      <securitiesExchangeName>NASDAQ</securitiesExchangeName>
    </securitiesInformation>
    <securitiesToBeSold>
      <securitiesClassTitle>Class A</securitiesClassTitle>
      <acquiredDate>07/19/2021</acquiredDate>
      <natureOfAcquisitionTransaction>Private Placement</natureOfAcquisitionTransaction>
      <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
      <isGiftTransaction>N</isGiftTransaction>
      <amountOfSecuritiesAcquired>6793</amountOfSecuritiesAcquired>
      <paymentDate>07/19/2021</paymentDate>
      <natureOfPayment>Cash</natureOfPayment>
    </securitiesToBeSold>
    <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
    <noticeSignature>
      <noticeDate>01/10/2025</noticeDate>
      <planAdoptionDates>
        <planAdoptionDate>06/10/2024</planAdoptionDate>
      </planAdoptionDates>
      <signature>Darshana Zaveri</signature>
    </noticeSignature>
  </formData>
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</SEC-DOCUMENT>
