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Summary of Significant Accounting Policies - Additional Information (Details) - USD ($)
12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Summary Of Significant Accounting Policies [Line Items]    
Cash equivalents   $ 0
Spero Potentiator Australia Pty Limited [Member] | Research and Development Expenses [Member]    
Summary Of Significant Accounting Policies [Line Items]    
Percentage of refundable tax incentive 43.50%