<SEC-DOCUMENT>0001719755-18-000003-index.html : 20180214
<SEC-HEADER>0001719755-18-000003.hdr.sgml : 20180214
<ACCEPTANCE-DATETIME>20180213201042
ACCESSION NUMBER:		0001719755-18-000003
CONFORMED SUBMISSION TYPE:	SC 13G
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20180214
DATE AS OF CHANGE:		20180213

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Spero Therapeutics, Inc.
		CENTRAL INDEX KEY:			0001701108
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-90168
		FILM NUMBER:		18606459

	BUSINESS ADDRESS:	
		STREET 1:		675 MASSACHUSETTS AVENUE
		STREET 2:		14TH FLOOR
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02139
		BUSINESS PHONE:		857-242-1600

	MAIL ADDRESS:	
		STREET 1:		675 MASSACHUSETTS AVENUE
		STREET 2:		14TH FLOOR
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02139

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Spero Therapeutics, LLC
		DATE OF NAME CHANGE:	20170316

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			GV 2015, L.P.
		CENTRAL INDEX KEY:			0001719755
		IRS NUMBER:				472144612
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G

	BUSINESS ADDRESS:	
		STREET 1:		1600 AMPHITHEATRE PARKWAY
		CITY:			MOUNTAIN VIEW
		STATE:			CA
		ZIP:			94043
		BUSINESS PHONE:		650-335-5278

	MAIL ADDRESS:	
		STREET 1:		1600 AMPHITHEATRE PARKWAY
		CITY:			MOUNTAIN VIEW
		STATE:			CA
		ZIP:			94043
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC 13G
<SEQUENCE>1
<FILENAME>a2018schedule13g-spero.htm
<DESCRIPTION>SC 13G
<TEXT>
Document 1 - file: a2018schedule13g-spero.htm

</DOCUMENT>
</SEC-DOCUMENT>