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Fair Value Measurements and Marketable Securities (Tables) | 3 Months Ended | 12 Months Ended
--- | --- | ---
Mar. 31, 2018 | Dec. 31, 2017
Fair Value Disclosures [Abstract] |  |
Summary of Financial Assets and Liabilities Measured at Fair Value Recurring Basis | The following tables present information about the Company’s assets and liabilities that are measured at fair value on a recurring basis (in thousands):
|  | Fair Value Measurements at March 31, 2018 Using: |
|  | Level 1 |  |  | Level 2 |  |  | Level 3 |  |  | Total |
Assets: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Cash equivalents: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Money market funds |  | $ | — |  |  | $ | 44,083 |  |  | $ | — |  |  | $ | 44,083 |
U.S. commercial paper |  |  | — |  |  |  | 3,996 |  |  |  | — |  |  |  | 3,996 |
Total cash equivalents |  |  | — |  |  |  | 48,079 |  |  |  | — |  |  |  | 48,079 |
Marketable securities: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
U.S. government securities |  |  | — |  |  |  | 8,919 |  |  |  | — |  |  |  | 8,919 |
U.S. corporate bonds |  |  | — |  |  |  | 7,976 |  |  |  | — |  |  |  | 7,976 |
U.S. commercial paper |  |  | — |  |  |  | 5,946 |  |  |  | — |  |  |  | 5,946 |
Total marketable securities |  |  | — |  |  |  | 22,841 |  |  |  | — |  |  |  | 22,841 |
Total cash equivalents and marketable securities |  | $ | — |  |  | $ | 70,920 |  |  | $ | — |  |  | $ | 70,920 |
Liabilities: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Derivative liabilities: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Anti-dilution rights |  | $ | — |  |  | $ | — |  |  | $ | 223 |  |  | $ | 223 |
Total derivative liabilities |  | $ | — |  |  | $ | — |  |  | $ | 223 |  |  | $ | 223 |
|  | Fair Value Measurements at December 31, 2017 Using: |
|  | Level 1 |  |  | Level 2 |  |  | Level 3 |  |  | Total |
Assets: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Cash equivalents: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Money market funds |  | $ | — |  |  | $ | 83,121 |  |  | $ | — |  |  | $ | 83,121 |
|  | $ | — |  |  | $ | 83,121 |  |  | $ | — |  |  | $ | 83,121 |
Liabilities: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Derivative liabilities: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Anti-dilution rights |  | $ | — |  |  | $ | — |  |  | $ | 223 |  |  | $ | 223 |
|  | $ | — |  |  | $ | — |  |  | $ | 223 |  |  | $ | 223 |
| The following tables present information about the Company’s assets and liabilities that are measured at fair value on a recurring basis (in thousands):
|  | Fair Value Measurements at December 31, 2017 Using: |
|  | Level 1 |  |  | Level 2 |  |  | Level 3 |  |  | Total |
Assets: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Cash equivalents: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Money market funds |  | $ | — |  |  | $ | 83,121 |  |  | $ | — |  |  | $ | 83,121 |
|  | $ | — |  |  | $ | 83,121 |  |  | $ | — |  |  | $ | 83,121 |
Liabilities: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Derivative liabilities: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Anti-dilution rights |  | $ | — |  |  | $ | — |  |  | $ | 223 |  |  | $ | 223 |
|  | $ | — |  |  | $ | — |  |  | $ | 223 |  |  | $ | 223 |
|  | Fair Value Measurements at December 31, 2016 Using: |
|  | Level 1 |  |  | Level 2 |  |  | Level 3 |  |  | Total |
Liabilities: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Derivative liabilities: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Anti-dilution rights |  | $ | — |  |  | $ | — |  |  | $ | 1,806 |  |  | $ | 1,806 |
Contingent prepayment option |  |  | — |  |  |  | — |  |  |  | 902 |  |  |  | 902 |
|  | $ | — |  |  | $ | — |  |  | $ | 2,708 |  |  | $ | 2,708 |
Roll Forward of the Fair values of Derivative Liabilities |  | The following table provides a roll forward of the aggregate fair values of the Company’s derivative liabilities, for which fair value was determined by Level 3 inputs (in thousands):
|  | Contingent Prepayment Options |  |  | Tranche Rights |  |  | Anti- Dilution Rights |  |  | Total |
Balance at December 31, 2015 |  | $ | — |  |  | $ | 2,404 |  |  | $ | 980 |  |  | $ | 3,384 |
Fair value at issuance |  |  | 908 |  |  |  | 909 |  |  |  | 1,780 |  |  |  | 3,597 |
Change in fair value |  |  | (6 | ) |  |  | (600 | ) |  |  | 26 |  |  |  | (580 | )
Settlement |  |  | — |  |  |  | (2,713 | ) |  |  | (980 | ) |  |  | (3,693 | )
Balance at December 31, 2016 |  |  | 902 |  |  |  | — |  |  |  | 1,806 |  |  |  | 2,708 |
Change in fair value |  |  | 42 |  |  |  | — |  |  |  | (1,583 | ) |  |  | (1,541 | )
Settlement |  |  | (944 | ) |  |  | — |  |  |  | — |  |  |  | (944 | )
Balance at December 31, 2017 |  | $ | — |  |  | $ | — |  |  | $ | 223 |  |  | $ | 223 |
Summary of Gross Unrealized Gains and Losses of Marketable Securities | The following table summarizes the gross unrealized gains and losses of the Company’s marketable securities as of March 31, 2018 (in thousands):
|  | March 31, 2018 |
|  | Amortized Cost |  |  | Gross Unrealized Gains |  |  | Gross Unrealized Losses |  |  | Fair Value |
Assets: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
U.S. government securities |  | $ | 8,925 |  |  | $ | — |  |  | $ | (6 | ) |  | $ | 8,919 |
U.S. corporate bonds |  |  | 7,999 |  |  |  | — |  |  |  | (23 | ) |  |  | 7,976 |
U.S. commercial paper |  |  | 5,946 |  |  |  | — |  |  |  | — |  |  |  | 5,946 |
|  | $ | 22,870 |  |  | $ | — |  |  | $ | (29 | ) |  | $ | 22,841 |

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- Definition Tabular disclosure of the fair value measurement of liabilities using significant unobservable inputs (Level 3), a reconciliation of the beginning and ending balances, separately presenting changes attributable to the following: (1) total gains or losses for the period (realized and unrealized), segregating those gains or losses included in earnings (or changes in net assets), and gains or losses recognized in other comprehensive income (loss) and a description of where those gains or losses included in earnings (or changes in net assets) are reported in the statement of income (or activities); (2) purchases, sales, issues, and settlements (each type disclosed separately); and (3) transfers in and transfers out of Level 3 (for example, transfers due to changes in the observability of significant inputs) by class of liability. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 820 -SubTopic 10 -Section 50 -Paragraph 3 -URI http://asc.fasb.org/extlink&oid=66048111&loc=d3e19279-110258 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 820 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=66048111&loc=d3e19207-110258 + Details
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- Definition Tabular disclosure of assets and liabilities, including [financial] instruments measured at fair value that are classified in stockholders' equity, if any, that are measured at fair value on a recurring basis. The disclosures contemplated herein include the fair value measurements at the reporting date by the level within the fair value hierarchy in which the fair value measurements in their entirety fall, segregating fair value measurements using quoted prices in active markets for identical assets (Level 1), significant other observable inputs (Level 2), and significant unobservable inputs (Level 3). + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 820 -SubTopic 10 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=66048111&loc=d3e19190-110258 + Details
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