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Income Taxes - Net Deferred Tax Assets (Detail) - USD ($) $ in Thousands | Dec. 31, 2017 | Dec. 31, 2016 | Dec. 31, 2015
--- | --- | --- | ---
Income Tax Disclosure [Abstract] |  |  |
Net operating loss carryforwards | $ 21,754 | $ 16,406 |
Research and development tax credit carryforwards | 2,022 | 697 |
Other | 743 | 49 |
Total deferred tax assets | 24,519 | 17,152 |
Valuation allowance | $ (24,519) | $ (17,152) | $ (6,157)

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- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences and carryforwards. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=84230637&loc=d3e32537-109319 + Details
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