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Income Taxes - Net Deferred Tax Assets (Detail) - USD ($) $ in Thousands | Dec. 31, 2021 | Dec. 31, 2020 | Dec. 31, 2019
--- | --- | --- | ---
Income Tax Disclosure [Abstract] |  |  |
Net operating loss carryforwards | $ 83,849 | $ 63,612 |
Research and development tax credit carryforwards | 12,375 | 8,024 |
Other | 6,220 | 3,403 |
Total deferred tax assets | 102,444 | 75,039 |
Valuation allowance | (102,444) | (75,039) | $ (51,980)
Net deferred tax assets | $ 0 | $ 0 |

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