EX-32 8 spro-ex32.htm EX-32

Exhibit 32

CERTIFICATIONS UNDER SECTION 906

Pursuant to section 906 of the Sarbanes-Oxley Act of 2002 (subsections (a) and (b) of section 1350, chapter 63 of title 18, United States Code), each of the undersigned officers of Spero Therapeutics, Inc., a Delaware corporation (the “Company”), does hereby certify, to such officer’s knowledge, that:

The Quarterly Report for the quarter ended September 30, 2024 (the “Form 10-Q”) of the Company fully complies with the requirements of Section 13(a) or 15(d) of the Securities Exchange Act of 1934, and the information contained in the Form 10-Q fairly presents, in all material respects, the financial condition and results of operations of the Company.

Dated: November 14, 2024 | /s/ Satyavrat Shukla
| Satyavrat Shukla
| President and Chief Executive Officer
| (Principal Executive Officer)

Dated: November 14, 2024 | /s/ Esther Rajavelu
| Esther Rajavelu
| Chief Financial Officer, Chief Business Officer and Treasurer
| (Principal Financial Officer and Principal Accounting Officer)