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Collaboration and License Agreements (Details) - USD ($) $ in Thousands				1 Months Ended		3 Months Ended			6 Months Ended
	Nov. 07, 2022	Sep. 14, 2018	Sep. 14, 2018	May 31, 2024	Jun. 30, 2022	Jun. 30, 2025	Jun. 30, 2024	Mar. 31, 2024	Jun. 30, 2025	Jun. 30, 2024	Dec. 31, 2024	Aug. 31, 2024	Nov. 30, 2023	Dec. 31, 2021	Dec. 31, 2020
Collaboration agreement
Revenue recognized						$ 1,907	$ 6,772		$ 3,536	$ 8,697
Proceeds from issuance of private placement								$ 19,996
Income expense in change in fair value of the stock price appreciation milestones						2,898	6,656		6,557	9,720
Candidate 2
Collaboration agreement
Clinical development milestone fees				$ 5,000
Ono Pharmaceutical Company Ltd
Collaboration agreement
Non-refundable upfront payments recorded as deferred revenue		$ 10,000
Non-refundable upfront payments recorded as deferred revenue		10,000	$ 10,000
Aggregate research and development fees payments receivable		20,000	20,000
Collaborative arrangement potential additional milestones		$ 44,500	44,500
Transaction price of the agreement			54,500
Revenue recognized						1,900	6,800		3,500	8,700
Ono Pharmaceutical Company Ltd | Candidate 1
Collaboration agreement
Percentage of reduction on milestone payments		50.00%
Ono Pharmaceutical Company Ltd | Candidate 2
Collaboration agreement
Milestone payments		$ 10,000	10,000
Milestone payment under Deferred revenue			10,000
Collaborative arrangement annual payments receivable recorded as deferred revenue			$ 5,000
Contra research and development expenses						1,300	1,100		3,300	2,000
Option exercise payment	$ 12,500
Ono Pharmaceutical Company Ltd | Minimum | Candidate 1
Collaboration agreement
Profits and losses sharing percentage					50.00%
Collaborative arrangement potential additional milestones					$ 9,300								$ 1,400
Ono Pharmaceutical Company Ltd | Minimum | Candidate 3
Collaboration agreement
Collaborative arrangement potential additional milestones						6,500			6,500			$ 7,300
Ono Pharmaceutical Company Ltd | Maximum | Candidate 1
Collaboration agreement
Collaborative arrangement potential additional milestones					$ 29,300								$ 30,700
Ono Pharmaceutical Company Ltd | Maximum | Candidate 2
Collaboration agreement
Aggregate milestone payments		$ 843,000
Ono Pharmaceutical Company Ltd | Maximum | Candidate 3
Collaboration agreement
Collaborative arrangement potential additional milestones						44,500			44,500			$ 38,000
Amended Mskcc License
Collaboration agreement
Enterprise value milestone payment						75,000			75,000
Stock price appreciation milestone payable														$ 20,000
Enterprise value milestones liability at fair value						300			300		$ 500
Amended MSK License
Collaboration agreement
Income expense in change in fair value of the stock price appreciation milestones						$ 100	$ 1,600		$ 200	$ 200
Ono Letter Agreement | Ono Pharmaceutical Company Ltd
Collaboration agreement
Milestone payments															$ 10,000

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