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Convertible Preferred Stock and Stockholders' Equity (Details) - USD ($)
$ / shares in Units, $ in Millions
 1 Months Ended 3 Months Ended 6 Months Ended 12 Months Ended
Mar. 31, 2024
Apr. 30, 2023
Jan. 31, 2021
Nov. 30, 2016
Mar. 31, 2024
Jun. 30, 2025
Dec. 31, 2024
May 02, 2017
Convertible preferred stock                
Preferred stock, par value (in dollars per share)           $ 0.001 $ 0.001  
Employee And Non Employee Stock Option                
Convertible preferred stock                
Unrecognized compensation cost related to outstanding options           $ 8.6    
Expected recognition weighted average period of unrecognized compensation cost           1 year 7 months 6 days    
Restricted Stock Units (RSUs)                
Convertible preferred stock                
Expected recognition weighted average period of unrecognized compensation cost           1 year 7 months 6 days    
Unrecognized compensation cost related to unvested restricted shares           $ 21.8    
Pre-Funded Warrants                
Convertible preferred stock                
Number of shares to be purchased 3,636,364   257,310   3,636,364 3,893,674    
Purchase price of prefunded warrants $ 5.499   $ 85.499          
Exercise price of warrants $ 0.001   $ 0.001   $ 0.001      
Terms of exercise     The Pre-Funded Warrants are exercisable at any time after the date of issuance. A holder of Pre-Funded Warrants may not exercise the Pre-Funded Warrant if the holder, together with its affiliates, would beneficially own more than 9.99% of the number of shares of the Company’s common stock outstanding immediately after giving effect to such exercise. A holder of Pre-Funded Warrants may increase or decrease this percentage not in excess of 19.99% by providing at least 61 days’ prior notice to the Company.          
Maximum percentage of common stock ownership together with affiliates allowable after exercise of prefunded warrants     9.99%          
Maximum percentage of common stock ownership after change upon notice     19.99%          
Common Stock                
Convertible preferred stock                
Public offering of common stock, net of issuance costs (in shares)         14,545,454      
Conversion of preferred shares to common stock   167,205         30,110  
Non-Voting Class A Preferred Stock | Redmile Group, LLC and Affiliates                
Convertible preferred stock                
Terms of conversion           The Class A Preferred were purchased exclusively by entities affiliated with Redmile Group, LLC (collectively, Redmile). The terms of the CoD prohibited Redmile from converting the Class A Preferred into shares of the Company’s common stock if, as a result of conversion, Redmile, together with its affiliates, would own more than 9.99% of the Company’s common stock then issued and outstanding (the Redmile Percentage Limitation), which percentage could change at Redmile’s election upon 61 days’ notice to the Company to (i) any other number less than or equal to 19.99% or (ii) subject to approval of the Company’s stockholders to the extent required in accordance with the Nasdaq Global Market rules, any number in excess of 19.99%. On May 2, 2017, the Company’s stockholders approved the issuance of up to an aggregate of 14,097,745 shares of common stock upon the conversion of the outstanding shares of Class A Preferred. As a result, Redmile has the right to increase the Redmile Percentage Limitation to any percentage in excess of 19.99% at its election.    
Non-Voting Class A Preferred Stock | Maximum                
Convertible preferred stock                
Number of shares to be issued upon conversion               14,097,745
Non-Voting Class A Preferred Stock | Maximum | Redmile Group, LLC and Affiliates                
Convertible preferred stock                
Percentage of common stock ownership upon preferred stock conversion       9.99%        
Preferred shares converted into common stock percentage of ownership change upon notice       19.99%        
Convertible Preferred Stock                
Convertible preferred stock                
Preferred stock, issued shares           2,755,086 2,755,086  
Percentage of common stock ownership upon preferred stock conversion   14.99%            
Conversion of preferred shares to common stock   33,441         6,022  
Convertible Preferred Stock | Redmile Group, LLC and Affiliates                
Convertible preferred stock                
Percentage of common stock ownership upon preferred stock conversion       19.99%        
November 2016 Placement | Common Stock                
Convertible preferred stock                
Share issue price (in dollars per share)       $ 2.66        
Public offering of common stock, net of issuance costs (in shares)       7,236,837        
November 2016 Placement | Non-Voting Class A Preferred Stock                
Convertible preferred stock                
Preferred stock, issued shares       2,819,549        
Share issue price (in dollars per share)       $ 13.3        
Preferred stock, par value (in dollars per share)       0.001        
Conversion price       $ 2.66