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Segment Reporting - Schedule of Segment Profit or Loss, Including Segment Expenses (Details) - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2025
Mar. 31, 2025
Jun. 30, 2024
Mar. 31, 2024
Jun. 30, 2025
Jun. 30, 2024
Segment Reporting Information [Line Items]            
Collaboration revenue $ 1,907   $ 6,772   $ 3,536 $ 8,697
Type of Revenue [Extensible List] us-gaap:LicenseMember us-gaap:LicenseMember us-gaap:LicenseMember us-gaap:LicenseMember us-gaap:LicenseMember us-gaap:LicenseMember
Less:            
Personnel costs $ 10,682   $ 10,654   $ 22,386 $ 22,958
Clinical programs 5,778   6,512   12,061 11,698
Research activities 1,870   3,807   4,306 6,529
Facilities costs 5,884   7,028   11,964 13,662
Other segment expenses [1] 14,661   23,854   31,067 50,001
Total operating expenses 38,875   51,855   81,784 104,848
Loss from operations (36,968)   (45,083)   (78,248) (96,151)
Other income (expense):            
Interest income (2,921)   (4,827)   (6,257) (8,976)
Change in fair value of stock price appreciation milestones 73   (1,556)   (207) (162)
Other income (50)   (273)   (93) (582)
Total other income (2,898)   (6,656)   (6,557) (9,720)
Net loss $ (34,070) $ (37,621) $ (38,427) $ (48,004) $ (71,691) $ (86,431)
[1] Other segment expenses include stock compensation expense, depreciation, legal fees, general & administrative expenses, and corporate expenses.