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v3.25.3

Segment Reporting - Schedule of Segment Profit or Loss, Including Segment Expenses (Details) - USD ($) $ in Thousands | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 30, 2025 | Jun. 30, 2025 | Mar. 31, 2025 | Sep. 30, 2024 | Jun. 30, 2024 | Mar. 31, 2024 | Sep. 30, 2025 | Sep. 30, 2024
Segment Reporting Information [Line Items] |  |  |  |  |  |  |  |  |
Collaboration revenue |  | $ 1,741 |  |  | $ 3,074 |  |  | $ 5,277 | $ 11,771
Type of Revenue [Extensible List] |  | us-gaap:LicenseMember |  |  | us-gaap:LicenseMember |  |  | us-gaap:LicenseMember | us-gaap:LicenseMember
Less: |  |  |  |  |  |  |  |  |
Personnel costs |  | $ 10,997 |  |  | $ 10,420 |  |  | $ 33,383 | $ 33,378
Clinical programs |  | 6,065 |  |  | 7,343 |  |  | 18,126 | 19,041
Research activities |  | 1,100 |  |  | 4,596 |  |  | 5,406 | 11,125
Facilities costs |  | 6,113 |  |  | 6,785 |  |  | 18,078 | 20,446
Other segment expenses | [1] | 12,201 |  |  | 26,307 |  |  | 43,267 | 76,309
Total operating expenses |  | 36,476 |  |  | 55,451 |  |  | 118,260 | 160,299
Loss from operations |  | (34,735) |  |  | (52,377) |  |  | (112,983) | (148,528)
Other income (expense): |  |  |  |  |  |  |  |  |
Interest income |  | 2,575 |  |  | 4,438 |  |  | 8,832 | 13,414
Change in fair value of stock price appreciation milestones |  | (90) |  |  | (13) |  |  | 117 | 149
Other income |  | 0 |  |  | 274 |  |  | 93 | 856
Total other income |  | 2,485 |  |  | 4,699 |  |  | 9,042 | 14,419
Net loss |  | $ (32,250) | $ (34,070) | $ (37,621) | $ (47,678) | $ (38,427) | $ (48,004) | $ (103,941) | $ (134,109)
[1] | Other segment expenses include stock compensation expense, depreciation, legal fees, general & administrative expenses, and corporate expenses.

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