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v3.25.3

Segment Reporting (Tables) | 9 Months Ended
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Sep. 30, 2025
Segment Reporting [Abstract] |
Schedule of segment profit or loss, including segment expenses | The table below is a summary of the segment profit or loss, including significant segment expenses (in thousands):
|  | Three Months Ended September 30, |  |  | Nine Months Ended September 30, |
|  | 2025 |  |  | 2024 |  |  | 2025 |  |  | 2024 |
Collaboration revenue |  | $ | 1,741 |  |  | $ | 3,074 |  |  | $ | 5,277 |  |  | $ | 11,771 |
Less: |  |  |  |  |  |  |  |  |  |  |  |
Personnel costs |  |  | 10,997 |  |  |  | 10,420 |  |  |  | 33,383 |  |  |  | 33,378 |
Clinical programs |  |  | 6,065 |  |  |  | 7,343 |  |  |  | 18,126 |  |  |  | 19,041 |
Research activities |  |  | 1,100 |  |  |  | 4,596 |  |  |  | 5,406 |  |  |  | 11,125 |
Facilities costs |  |  | 6,113 |  |  |  | 6,785 |  |  |  | 18,078 |  |  |  | 20,446 |
Other segment expenses (1) |  |  | 12,201 |  |  |  | 26,307 |  |  |  | 43,267 |  |  |  | 76,309 |
Total operating expenses |  |  | 36,476 |  |  |  | 55,451 |  |  |  | 118,260 |  |  |  | 160,299 |
Loss from operations |  |  | (34,735 | ) |  |  | (52,377 | ) |  |  | (112,983 | ) |  |  | (148,528 | )
Other income (expense): |  |  |  |  |  |  |  |  |  |  |  |
Interest income |  |  | 2,575 |  |  |  | 4,438 |  |  |  | 8,832 |  |  |  | 13,414 |
Change in fair value of stock price appreciation milestones |  |  | (90 | ) |  |  | (13 | ) |  |  | 117 |  |  |  | 149 |
Other income |  |  | — |  |  |  | 274 |  |  |  | 93 |  |  |  | 856 |
Total other income |  |  | 2,485 |  |  |  | 4,699 |  |  |  | 9,042 |  |  |  | 14,419 |
Net loss |  | $ | (32,250 | ) |  | $ | (47,678 | ) |  | $ | (103,941 | ) |  | $ | (134,109 | )
(1) Other segment expenses include stock compensation expense, depreciation, legal fees, general & administrative expenses, and corporate expenses.

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- Definition Tabular disclosure of the profit or loss and total assets for each reportable segment. An entity discloses certain information on each reportable segment if the amounts (a) are included in the measure of segment profit or loss reviewed by the chief operating decision maker or (b) are otherwise regularly provided to the chief operating decision maker, even if not included in that measure of segment profit or loss. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 25 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-25 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 22 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-22 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 30 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-30 + Details
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