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Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($)
$ in Thousands
 3 Months Ended 9 Months Ended
Sep. 30, 2025
Sep. 30, 2024
Sep. 30, 2025
Sep. 30, 2024
Income Statement [Abstract]        
Collaboration revenue $ 1,741 $ 3,074 $ 5,277 $ 11,771
Type of Revenue [Extensible List] us-gaap:LicenseMember us-gaap:LicenseMember us-gaap:LicenseMember us-gaap:LicenseMember
Operating expenses:        
Research and development $ 25,838 $ 34,650 $ 82,404 $ 101,392
General and administrative 10,638 20,801 35,856 58,907
Total operating expenses 36,476 55,451 118,260 160,299
Loss from operations (34,735) (52,377) (112,983) (148,528)
Other income (expense):        
Interest income 2,575 4,438 8,832 13,414
Change in fair value of stock price appreciation milestones (90) (13) 117 149
Other income 0 274 93 856
Total other income 2,485 4,699 9,042 14,419
Net loss (32,250) (47,678) (103,941) (134,109)
Other comprehensive (loss):        
Unrealized loss on available-for-sale securities, net 91 1,257 (115) 820
Comprehensive loss $ (32,159) $ (46,421) $ (104,056) $ (133,289)
Net loss per common share, basic $ (0.27) $ (0.4) $ (0.88) $ (1.19)
Net loss per common share, diluted $ (0.27) $ (0.4) $ (0.88) $ (1.19)
Weighted-average common shares outstanding used to compute diluted net loss per share 118,998,693 117,769,161 118,636,375 112,305,430
Weighted-average common shares outstanding used to compute basic net loss per share 118,998,693 117,769,161 118,636,375 112,305,430