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Segment Reporting - Schedule of Segment Profit or Loss, Including Segment Expenses (Details) - USD ($)
$ in Thousands
 3 Months Ended 9 Months Ended
Sep. 30, 2025
Jun. 30, 2025
Mar. 31, 2025
Sep. 30, 2024
Jun. 30, 2024
Mar. 31, 2024
Sep. 30, 2025
Sep. 30, 2024
Segment Reporting Information [Line Items]                
Collaboration revenue $ 1,741     $ 3,074     $ 5,277 $ 11,771
Type of Revenue [Extensible List] us-gaap:LicenseMember     us-gaap:LicenseMember     us-gaap:LicenseMember us-gaap:LicenseMember
Less:                
Personnel costs $ 10,997     $ 10,420     $ 33,383 $ 33,378
Clinical programs 6,065     7,343     18,126 19,041
Research activities 1,100     4,596     5,406 11,125
Facilities costs 6,113     6,785     18,078 20,446
Other segment expenses [1] 12,201     26,307     43,267 76,309
Total operating expenses 36,476     55,451     118,260 160,299
Loss from operations (34,735)     (52,377)     (112,983) (148,528)
Other income (expense):                
Interest income 2,575     4,438     8,832 13,414
Change in fair value of stock price appreciation milestones (90)     (13)     117 149
Other income 0     274     93 856
Total other income 2,485     4,699     9,042 14,419
Net loss $ (32,250) $ (34,070) $ (37,621) $ (47,678) $ (38,427) $ (48,004) $ (103,941) $ (134,109)
[1] Other segment expenses include stock compensation expense, depreciation, legal fees, general & administrative expenses, and corporate expenses.