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Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
 9 Months Ended
Sep. 30, 2025
Sep. 30, 2024
Operating activities    
Net loss $ (103,941) $ (134,109)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 9,838 14,149
Stock-based compensation 19,396 32,376
Accretion and amortization of premiums and discounts on investments, net (2,725) (7,550)
Deferred revenue (389) (685)
Change in fair value of stock price appreciation milestones (117) (149)
(Gain) loss on disposal of property and equipment (36) 942
Changes in operating assets and liabilities:    
Accounts receivable 2,857 (1,701)
Prepaid expenses and other assets 4,165 5,294
Accounts payable and accrued expenses (9,892) (2,316)
Right-of-use assets and lease liabilities, net (1,926) (1,326)
Net cash used in operating activities (82,770) (95,075)
Investing activities    
Proceeds from sale of property and equipment 125 0
Purchases of property and equipment (4,761) (632)
Purchases of investments (157,412) (279,745)
Maturities of investments 245,584 269,779
Net cash provided by (used in) investing activities 83,536 (10,598)
Financing activities    
Issuance of common stock from equity incentive plans, net of issuance costs 0 295
Proceeds from public offering of common stock, net of issuance costs 0 74,531
Proceeds from issuance of pre-funded warrants, net of issuance costs 0 19,996
Proceeds from FT819 CIRM award 0 1,940
Proceeds from FT836 CIRM award 3,800 0
Net cash provided by financing activities 3,800 96,762
Net change in cash, cash equivalents and restricted cash 4,566 (8,911)
Cash, cash equivalents and restricted cash at beginning of the period 46,283 57,047
Cash, cash equivalents and restricted cash at end of the period 50,849 48,136
Supplemental schedule of noncash investing and financing activities    
Purchases of property and equipment in accounts payable $ 398 $ 16