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CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE INCOME (LOSS) (unaudited) - USD ($) | 3 Months Ended | 9 Months Ended | 12 Months Ended
--- | --- | --- | ---
Sep. 30, 2019 | Sep. 30, 2018 | Sep. 30, 2019 | Sep. 30, 2018 | Dec. 31, 2018 | Dec. 31, 2017
Operating expenses |  |  |  |  |  |
Research and development | $ 513,004 | $ 67,291 | $ 1,522,031 | $ 92,291 | $ 329,966 | $ 311,302
General and administrative | 990,110 | 978,329 | 3,267,037 | 3,284,880 | 4,362,557 | 3,547,927
Total operating expenses | 1,503,114 | 1,045,620 | 4,789,068 | 3,377,171 | 4,692,523 | 3,859,229
Operating loss | (1,503,114) | (1,045,620) | (4,789,068) | (3,377,171) | (4,692,523) | (3,859,229)
Other expense (income) |  |  |  |  |  |
Change in fair value of derivative liabilities | 3,126,464 | 1,050,729 | (2,024,660) | 1,653,477 | 6,503,174 | (767,198)
Fair value of derivative liabilities in excess of proceeds |  |  | 322,644 | 7,174,634 | 7,174,634 |
Financing transaction costs |  |  |  | 137,192 | 137,192 |
Loss on extinguishment of secured convertible promissory note - related party |  |  |  | 590,392 | 590,392 |
Interest expense | 301,547 | 0 | 711,575 | 37,708 | 94,763 | 667
Interest income |  |  |  | (74) | (84) |
Total other expense (income) | 3,428,011 | 1,050,729 | (990,441) | 9,593,329 |  |
Loss before income taxes | (4,931,125) | (2,096,349) | (3,798,627) | (12,970,500) | (19,192,594) | (3,092,698)
Provision for income taxes |  |  | 1,600 | 1,642 | 1,642 | 1,600
Net Loss and comprehensive loss | $ (4,931,125) | $ (2,096,349) | $ (3,800,227) | $ (12,972,142) | (19,194,236) | (3,094,298)
Less: Preferred deemed dividend |  |  |  |  |  | 1,044,000
Net loss applicable to common shareholders |  |  |  |  | $ (19,194,236) | $ (4,138,298)
Loss per common share: |  |  |  |  |  |
Basic (in dollars per share) | $ (0.04) | $ (0.02) | $ (0.03) | $ (0.11) |  |
Diluted (in dollars per share) | $ (0.04) | $ (0.02) | $ (0.03) | $ (0.11) |  |
Weighted average shares of common stock outstanding used to compute earnings per share: |  |  |  |  |  |
Basic (in shares) | 133,001,746 | 131,445,057 | 132,885,675 | 117,434,563 |  |
Diluted (in shares) | 133,001,746 | 131,445,057 | 167,690,989 | 117,434,563 |  |
Basic and diluted net loss per common share (in dollars per share) |  |  |  |  | $ (0.16) | $ (0.11)
Weighted average shares of common stock outstanding: basic and diluted (in shares) |  |  |  |  | 121,154,334 | 27,906,090

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- Definition Number of [basic] shares or units, after adjustment for contingently issuable shares or units and other shares or units not deemed outstanding, determined by relating the portion of time within a reporting period that common shares or units have been outstanding to the total time in that period. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 260 -SubTopic 10 -Section 45 -Paragraph 10 -URI http://asc.fasb.org/extlink&oid=109260490&loc=d3e1448-109256 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 260 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=6371337&loc=d3e3550-109257 + Details
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- References No definition available. + Details
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