<SEC-DOCUMENT>0001516551-24-000112-index.html : 20241107
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<ACCEPTANCE-DATETIME>20241107161849
ACCESSION NUMBER:		0001516551-24-000112
CONFORMED SUBMISSION TYPE:	S-8
PUBLIC DOCUMENT COUNT:		5
FILED AS OF DATE:		20241107
DATE AS OF CHANGE:		20241107
EFFECTIVENESS DATE:		20241107

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Skye Bioscience, Inc.
		CENTRAL INDEX KEY:			0001516551
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		IRS NUMBER:				450692882
		STATE OF INCORPORATION:			NV
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-8
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-283068
		FILM NUMBER:		241436101

	BUSINESS ADDRESS:	
		STREET 1:		11250 EL CAMINO REAL, SUITE 100
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92130
		BUSINESS PHONE:		(858) 410-0266

	MAIL ADDRESS:	
		STREET 1:		11250 EL CAMINO REAL, SUITE 100
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92130

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Emerald Bioscience, Inc.
		DATE OF NAME CHANGE:	20190325

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Nemus Bioscience, Inc.
		DATE OF NAME CHANGE:	20141030

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	LOAD GUARD LOGISTICS, INC.
		DATE OF NAME CHANGE:	20121107
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-8
<SEQUENCE>1
<FILENAME>skye-11072024_sx8arplan.htm
<DESCRIPTION>S-8
<TEXT>
Document 1 - file: skye-11072024_sx8arplan.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-FILING FEES
<SEQUENCE>2
<FILENAME>ex107filingfeetable1.htm
<DESCRIPTION>EX-FILING FEES
<TEXT>
Document 2 - file: ex107filingfeetable1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>3
<FILENAME>ex51opinionoffennemorecrai.htm
<DESCRIPTION>EX-5.1
<TEXT>
Document 3 - file: ex51opinionoffennemorecrai.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.2
<SEQUENCE>4
<FILENAME>ex232consentofmarcumllp1.htm
<DESCRIPTION>EX-23.2
<TEXT>
Document 4 - file: ex232consentofmarcumllp1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>5
<FILENAME>fennemore.jpg
<TEXT>
Document 5 - file: fennemore.jpg

</DOCUMENT>
</SEC-DOCUMENT>