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STOCK BASED COMPENSATION (Details Narrative) - USD ($) |  | 12 Months Ended |  |
--- | --- | --- | --- | ---
May 18, 2016 | Dec. 31, 2016 | Dec. 31, 2015 | Jan. 01, 2017 | Sep. 28, 2010
Share-based Compensation |  | $ 876,189 | $ 840,103 |  |
Number of shares granted |  | 185,245 |  |  |
Vesting period |  | 1 year 10 months 28 days |  |  |
Number of unvested options outstanding |  | 105,926 |  |  |
Unrecognized compensation cost |  | $ 976,056 |  |  |
Weighted average exercise price of stock options exercisable |  | $ 37.80 |  |  |
Weighted average exercise price of stock options granted | $ 3.90 | $ 3.90 |  |  |
Subsequent Event [Member] | Stock Option and Incentive Plan 2010 [Member] |  |  |  |  |
Number of shares available for grant |  |  |  | 151,477 |
Stock Option and Incentive Plan 2010 [Member] |  |  |  |  |
Shares held in employee stock option plan suspense shares |  |  |  |  | 66,667
Number of shares available for grant |  | 156,388 |  |  |
Stock Option Plan 2010 [Member] | Shu-Chih Chen [Member] |  |  |  |  |
Vesting period |  | 2 years |  |  |
Number of shares covered by options |  | 10,101 |  |  |
Employees and Directors [Member] |  |  |  |  |
Number of shares granted |  | 185,245 |  |  |
Vesting period |  | 1 year |  |  |
Senior Officers [Member] | Stock Option Plan 2010 [Member] |  |  |  |  |
Vesting period |  |  | 4 years |  |
Senior Officers [Member] | Stock Option Plan 2010 [Member] | Mr. Guse [Member] |  |  |  |  |
Number of shares available for grant |  |  | 13,333 |  |
Senior Officers [Member] | Stock Option Plan 2010 [Member] | Dr. Quay [Member] |  |  |  |  |
Vesting period |  | 2 years |  |  |

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