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Note 11 - Income Taxes - Effective Income Tax Rate Reconciliation (Details) - USD ($) | 12 Months Ended
--- | ---
Dec. 31, 2018 | Dec. 31, 2017
Expected federal income tax benefit | $ (2,395,036) | $ (2,761,678)
Stock compensation | 169,957 | 197,336
Other permanent items | 1,616 | 2,668
Effect of change in valuation allowance | 2,223,463 | (15,344,015)
Prior year true-up |  | (126,031)
Tax rate change |  | 1,912,427
Effect of NOL limitation |  | 16,119,293
Actual federal income tax benefit | $ 0 | $ 0

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