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Note 9 - Stockholders' Equity (Tables) | 12 Months Ended
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Dec. 31, 2018
Notes Tables |
Schedule of Warrants Activity [Table Text Block] |
|  | Shares |  |  | Weighted Average Exercise Price |
Outstanding as of January 1, 2017 |  |  |  |  |  |  |  |
Warrants granted |  |  | 488,611 |  |  | $ | 11.25 |
Warrants exercised |  |  | (488,611 | ) |  |  | 3.12 |
Outstanding as of December 31, 2017 |  |  |  |  |  |  |  |
Schedule of Stockholders' Equity Note, Warrants or Rights [Table Text Block] |
|  | Outstanding Warrants to Purchase Shares |  |  | Exercise Price |  | Expiration Date
2014 public offering |  |  | 6,483 |  |  | $ | 540.00 |  | January 29, 2019
2018 warrants |  |  | 3,869,216 |  |  |  | 4.05 |  | May 30, 2022
|  |  | 3,875,699 |  |  |  |  |  |
Warrant [Member] |
Notes Tables |
Fair Value Measurement Inputs and Valuation Techniques [Table Text Block] |
Initial valuation |  |  |  |
Common stock price |  | $9.00 |  |
Exercise price |  | $11.25 |  |
Expected volatility |  | 50% |  |
Dividend yield |  | 0% |  |
Risk-free interest rate | 0.79% | - | 1.88% |
Expected term (in years) | 0.24 | - | 5 |
June 30, 2017 valuation |  |  |  |
Common stock price |  | $6.00 |  |
Exercise price |  | $3.12 |  |
Expected volatility |  | 50% |  |
Dividend yield |  | 0% |  |
Risk-free interest rate | 0.79 | - | 1.88% |
Expected term (in years) | 0.08 | - | 4.76 |

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- Definition Tabular disclosure of input and valuation technique used to measure fair value and change in valuation approach and technique for each separate class of asset and liability measured on recurring and nonrecurring basis. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 820 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (bbb) -URI http://asc.fasb.org/extlink&oid=99377789&loc=d3e19207-110258 + Details
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- Definition Tabular disclosure of warrants or rights issued. Warrants and rights outstanding are derivative securities that give the holder the right to purchase securities (usually equity) from the issuer at a specific price within a certain time frame. Warrants are often included in a new debt issue to entice investors by a higher return potential. The main difference between warrants and call options is that warrants are issued and guaranteed by the company, whereas options are exchange instruments and are not issued by the company. Also, the lifetime of a warrant is often measured in years, while the lifetime of a typical option is measured in months. Disclose the title of issue of securities called for by warrants and rights outstanding, the aggregate amount of securities called for by warrants and rights outstanding, the date from which the warrants or rights are exercisable, and the price at which the warrant or right is exercisable. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5047-113901 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 235 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.4-08(i)) -URI http://asc.fasb.org/extlink&oid=26873400&loc=d3e23780-122690 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 505 -SubTopic 50 -Section S99 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6784392&loc=d3e188667-122775 Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 505 -SubTopic 50 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=68057994&loc=d3e25284-112666 + Details
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