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CONSOLIDATED STATEMENT OF SHAREHOLDERS` EQUITY - USD ($) | Preferred Stock [Member] | Common Stock [Member] | Additional Paid-in Capital [Member] | Retained Earnings [Member] | Total Shareholders Equity [Member] | Noncontrolling Interest [Member] | Total
--- | --- | --- | --- | --- | --- | --- | ---
BALANCE at Oct. 31, 2016 | $ 14,000 | $ 87,524 | $ 152,051,144 | $ (151,165,193) | $ 987,475 |  | $ 987,475
BALANCE (in Shares) at Oct. 31, 2016 | 140 | 8,752,387 |  |  |  |  |
Stock option compensation to employees and directors |  |  | 1,219,468 |  | 1,219,468 |  | 1,219,468
Stock options and warrants issued to consultants |  |  | 3,304 |  | 3,304 |  | 3,304
Common stock issued upon exercise of stock options |  | $ 402 | 6,871 |  | 7,273 |  | 7,273
Common stock issued upon exercise of stock options (in Shares) |  | 40,220 |  |  |  |  |
Stock award compensation to directors and employee pursuant to stock incentive plan |  | $ 2,000 | 452,000 |  | 454,000 |  | 454,000
Stock award compensation to directors and employee pursuant to stock incentive plan (in Shares) |  | 200,000 |  |  |  |  |
Common stock issued to consultants |  | $ 95 | 32,329 |  | 32,424 |  | 32,424
Common stock issued to consultants (in Shares) |  | 9,463 |  |  |  |  |
Redemption of convertible preferred stock | $ (14,000) |  | (3,486,000) |  | (3,500,000) |  | (3,500,000)
Redemption of convertible preferred stock (in Shares) | (140) |  |  |  |  |  |
Common stock issued to repay patent acquisition obligation |  | $ 9,476 | 2,842,818 |  | 2,852,294 |  | 2,852,294
Common stock issued to repay patent acquisition obligation (in Shares) |  | 947,606 |  |  |  |  |
Common stock issued in shareholder rights offering |  | $ 19,892 | 4,183,410 |  | 4,203,302 |  | 4,203,302
Common stock issued in shareholder rights offering (in Shares) |  | 1,989,207 |  |  |  |  |
Common stock issued in registered direct offering |  | $ 34,254 | 3,177,534 |  | 3,211,788 |  | 3,211,788
Common stock issued in registered direct offering (in Shares) |  | 3,425,376 |  |  |  |  |
Common stock issued in at-the-market offering |  | $ 12,385 | 3,448,201 |  | 3,460,586 |  | 3,460,586
Common stock issued in at-the-market offering (in Shares) |  | 1,238,500 |  |  |  |  |
Net Loss |  |  |  | (5,008,991) | (5,008,991) |  | (5,008,991)
BALANCE at Oct. 31, 2017 |  | $ 166,028 | 163,931,079 | (156,174,184) | 7,922,923 |  | 7,922,923
BALANCE (in Shares) at Oct. 31, 2017 |  | 16,602,759 |  |  |  |  |
Stock option compensation to employees and directors |  |  | 5,717,651 |  | 5,717,651 |  | 5,717,651
Stock options and warrants issued to consultants |  |  | 318,139 |  | 318,139 |  | 318,139
Common stock issued upon exercise of stock options |  | $ 766 | 57,372 |  | 58,138 |  | 58,138
Common stock issued upon exercise of stock options (in Shares) |  | 76,636 |  |  |  |  |
Stock award compensation to directors and employee pursuant to stock incentive plan |  | $ 15,000 | 2,844,824 |  | 2,859,824 |  | 2,859,824
Stock award compensation to directors and employee pursuant to stock incentive plan (in Shares) |  | 1,500,000 |  |  |  |  |
Common stock issued to consultants |  | $ 53 | 14,949 |  | 15,002 |  | 15,002
Common stock issued to consultants (in Shares) |  | 5,347 |  |  |  |  |
Common stock issued in at-the-market offering |  | $ 7,239 | 2,462,943 |  | 2,470,182 |  | 2,470,182
Common stock issued in at-the-market offering (in Shares) |  | 723,890 |  |  |  |  |
Issuance of noncontrolling interest in Certainty Therapeutics, Inc. |  |  | 68,974 |  | 68,974 | (4,318) | 64,656
Net Loss |  |  |  | (13,996,025) | (13,996,025) | (247,059) | (14,243,084)
BALANCE at Oct. 31, 2018 |  | $ 189,086 | $ 175,415,931 | $ (170,170,209) | $ 5,434,808 | $ (251,377) | $ 5,183,431
BALANCE (in Shares) at Oct. 31, 2018 |  | 18,908,632 |  |  |  |  |

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