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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) | 12 Months Ended
--- | ---
Oct. 31, 2019 | Oct. 31, 2018
Cash flows from operating activities: |  |
Net loss | $ (11,818,652) | $ (14,243,084)
Stock option compensation to employees and directors | 3,560,883 | 5,717,651
Stock options and warrants issued to consultants | 198,421 | 318,139
Restricted stock award compensation to employee pursuant to stock incentive plan | 1,954,441 | 2,859,824
Common stock issued to consultants |  | 15,002
Amortization of patents | 418,750 | 325,296
Depreciation of property and equipment | 47,558 | 18,435
Impairment in carrying amount of patent assets | 418,750 | 582,979
Issuance of noncontrolling interest in Certainty Therapeutics, Inc. expensed as a license fee |  | 64,656
Change in operating assets and liabilities: |  |
Receivables | 271,700 | (258,991)
Prepaid expenses and other current assets | (9,481) | (48,925)
Accounts payable | 3,805 | 101,688
Accrued expenses | 212,399 | 273,930
Net cash used in operating activities | (4,741,426) | (4,273,400)
Cash flows from investing activities: |  |
Disbursements to acquire short-term investments in certificates of deposit | (3,850,000) | (4,250,000)
Proceeds from maturities of short-term investments in certificates of deposit | 3,500,000 | 5,750,000
Purchase of property and equipment | (175,457) | (38,404)
Net cash (used in) provided by investing activities | (525,457) | 1,461,596
Cash flows from financing activities: |  |
Proceeds from sale of common stock in at-the-market offering | 5,527,428 | 2,470,182
Proceeds from sale of common stock pursuant to employee stock purchase plan | 39,086 |
Proceeds from settlement of shareholder derivative complaint | 14,034 |
Proceeds from exercise of stock options and warrants | 122,070 | 58,138
Net cash provided by financing activities | 5,702,618 | 2,528,320
Net increase (decrease) in cash and cash equivalents | 435,735 | (283,484)
Cash and cash equivalents at beginning of year | 3,055,890 | 3,339,374
Cash and cash equivalents at end of year | 3,491,625 | 3,055,890
Supplemental cash flow information: |  |
Cash proceeds from interest income | 55,729 | 12,684
Supplemental disclosure of non-cash investing activity: |  |
Disposal of fully depreciated property and equipment | (6,343) |
Supplemental disclosure of non-cash financing activity: |  |
Note receivable issued for settlement of shareholder derivative complaint | $ 31,236 |

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