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Summary of Significant Accounting Policies (Tables) | 9 Months Ended
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Sep. 30, 2013
Summary of Fair Value Measurement Financial Asset and Liabilities | Financial assets and liabilities subject to fair value measurements were as follows:
|  | Fair Value Measurements at September 30, 2013 |
|  | Total |  |  | Quoted Prices in Active Markets for Identical Assets |  |  | Significant Other Observable Inputs |  |  | Significant Unobservable Inputs |
|  |  | Level 1 |  |  | Level 2 |  |  | Level 3 |
Assets: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Cash and cash equivalents |  | $ | 7,522,029 |  |  | $ | 7,522,029 |  |  | $ | — |  |  | $ | — |
Money market funds |  |  | 26,047,169 |  |  |  | 26,047,169 |  |  |  | — |  |  |  | — |
Restricted cash |  |  | 404,850 |  |  |  | 404,850 |  |  |  | — |  |  |  | — |
Total assets |  | $ | 33,974,048 |  |  | $ | 33,974,048 |  |  | $ | — |  |  | $ | — |
Liabilities: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Preferred stock warrant liability |  | $ | (679,296 | ) |  | $ | — |  |  | $ | — |  |  | $ | (679,296 | )
|  | Fair Value Measurements at December 31, 2012 |
|  | Total |  |  | Quoted Prices in Active Markets for Identical Assets |  |  | Significant Other Observable Inputs |  |  | Significant Unobservable Inputs |
|  |  | Level 1 |  |  | Level 2 |  |  | Level 3 |
Assets: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Cash and cash equivalents |  | $ | 18,695,197 |  |  | $ | 18,695,197 |  |  | $ | — |  |  | $ | — |
Money market funds |  |  | 29,047,958 |  |  |  | 29,047,958 |  |  |  | — |  |  |  | — |
Restricted cash |  |  | 404,850 |  |  |  | 404,850 |  |  |  | — |  |  |  | — |
Total assets |  | $ | 48,148,005 |  |  | $ | 48,148,005 |  |  | $ | — |  |  | $ | — |
Liabilities: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Preferred stock warrant liability |  | $ | (52,947 | ) |  | $ | — |  |  | $ | — |  |  | $ | (52,947 | )
Summary of Preferred Stock Warrant Liability | The following table provides a rollforward of the Company’s preferred stock warrant liability, which was the only financial instrument measured at fair value on a recurring basis using significant unobservable inputs (Level 3) as defined in ASC 820:
Balance at December 31, 2012 |  | $ | (52,947 | )
Total unrealized gains (losses) included in earnings |  |  | (626,349 | )
Balance at September 30, 2013 |  | $ | (679,296 | )
Estimated Useful Lives | Depreciation and amortization are computed using the straight-line method over the following estimated useful lives:
Computer equipment |  | 3 years
Software |  | 3 years
Furniture |  | 10 years
Laboratory and office equipment |  | 5 years
Leasehold improvements |  | Shorter of lease term or useful life
Schedule of Dilutive Securities Excluded from Computation of Diluted Net Income Per Share | Basic and diluted income (loss) per common share is computed as follows:
|  | Three Months Ended September 30, |  |  | Nine Months Ended September 30, |
|  | 2013 |  |  | 2012 |  |  | 2013 |  |  | 2012 |
Net income (loss) |  | $ | 6,603,982 |  |  | $ | 2,600,514 |  |  | $ | 2,944,149 |  |  | $ | 10,466,582 |
Less: undistributed earnings allocated to participating securities |  |  | (6,434,756 | ) |  |  | (2,600,514 | ) |  |  | (2,944,149 | ) |  |  | (10,466,582 | )
Net income (loss) allocable to common shares |  | $ | 169,226 |  |  | $ | — |  |  | $ | — |  |  | $ | — |
Basic weighted average common shares outstanding |  |  | 1,184,507 |  |  |  | 1,092,307 |  |  |  | 1,463,798 |  |  |  | 1,078,145 |
Basic income (loss) per common share |  | $ | 0.14 |  |  | $ | — |  |  | $ | — |  |  | $ | — |
Net income (loss) |  | $ | 6,603,982 |  |  | $ | 2,600,514 |  |  | $ | 2,944,149 |  |  | $ | 10,466,582 |
Less: undistributed earnings allocated to participating securities and other add-backs to net income (loss) |  |  | (6,403,843 | ) |  |  | (2,600,514 | ) |  |  | (2,944,149 | ) |  |  | (10,466,582 | )
Net income (loss) allocable to common shares |  | $ | 200,139 |  |  | $ | — |  |  | $ | — |  |  | $ | — |
Basic weighted average common shares outstanding |  |  | 1,184,507 |  |  |  | 1,092,307 |  |  |  | 1,463,798 |  |  |  | 1,078,145 |
Effect of dilutive securities |  |  | 20,058,471 |  |  |  | 20,410,117 |  |  |  | 20,445,061 |  |  |  | 20,334,703 |
Diluted weighted average common shares outstanding |  |  | 21,242,978 |  |  |  | 21,502,424 |  |  |  | 21,908,859 |  |  |  | 21,412,848 |
Diluted income (loss) per common share |  | $ | 0.01 |  |  | $ | — |  |  | $ | — |  |  | $ | — |
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share | The following common stock equivalents are included in the calculation of diluted net income (loss) per share:
|  | Three Months Ended September 30, |  |  | Nine Months Ended September 30, |
|  | 2013 |  |  | 2012 |  |  | 2013 |  |  | 2012 |
Series A-1 Preferred Stock |  |  | 2,156,114 |  |  |  | 2,156,114 |  |  |  | 2,156,114 |  |  |  | 2,156,114 |
Series A-2 Preferred Stock |  |  | 392,274 |  |  |  | 392,274 |  |  |  | 392,274 |  |  |  | 392,274 |
Series B Preferred Stock |  |  | 4,336,037 |  |  |  | 4,336,037 |  |  |  | 4,336,037 |  |  |  | 4,336,037 |
Series C Preferred Stock |  |  | 5,909,906 |  |  |  | 5,909,906 |  |  |  | 5,909,906 |  |  |  | 5,909,906 |
Series D Preferred Stock |  |  | 769,468 |  |  |  | 769,468 |  |  |  | 769,468 |  |  |  | 769,468 |
Series D-2 Preferred Stock |  |  | 3,391,991 |  |  |  | 3,391,991 |  |  |  | 3,391,991 |  |  |  | 3,391,991 |
Warrants to purchase Series D-2 Preferred Stock |  |  | 180,784 |  |  |  | 180,784 |  |  |  | 180,784 |  |  |  | 180,784 |
Stock Options |  |  | 2,910,952 |  |  |  | 3,276,516 |  |  |  | 2,910,952 |  |  |  | 3,276,516 |
Summary of Significant Revenue [Member] |
Summary of Percentage of Customer Concentration | The following table represents the percentage of all significant revenue earned in the periods indicated:
|  | Three Months Ended September 30, |  |  | Nine Months Ended September 30, |
|  | 2013 |  |  | 2012 |  |  | 2013 |  |  | 2012 |
Servier |  |  | 71.3 | % |  |  | 14.2 | % |  |  | 58.8 | % |  |  | 12.6 | %
Boehringer |  |  | 11.5 | % |  |  | 15.6 | % |  |  | 15.9 | % |  |  | 17.2 | %
Gilead |  |  | 10.9 | % |  |  | 0.0 | % |  |  | 13.7 | % |  |  | 0.0 | %
Pfizer |  |  | 4.5 | % |  |  | 7.7 | % |  |  | 7.3 | % |  |  | 7.4 | %
Government Agencies |  |  | 0.6 | % |  |  | 3.5 | % |  |  | 2.6 | % |  |  | 6.9 | %
Eli Lilly |  |  | 0.9 | % |  |  | 59.0 | % |  |  | 1.6 | % |  |  | 55.7 | %
Summary of Significant Accounts Receivable[Member] |
Summary of Percentage of Customer Concentration | The following table represents the percentage of all significant accounts receivable:
|  | September 30, 2013 |  |  | December 31, 2012 |
Gilead |  |  | 51.2 | % |  |  | — |
Pfizer |  |  | 22.6 | % |  |  | 45.4 | %
Boehringer |  |  | 11.1 | % |  |  | 18.0 | %
Eli Lilly |  |  | 11.0 | % |  |  | 28.2 | %
Government Agencies |  |  | 4.0 | % |  |  | 8.4 | %

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