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Summary of Significant Accounting Policies (Tables) | 12 Months Ended
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Dec. 31, 2013
Summary of Fair Value Measurement Financial Asset and Liabilities | Financial assets and liabilities subject to fair value measurements were as follows:
|  | Fair Value Measurements at December 31, 2013 |
|  |  |  |  | Quoted Prices in Active Markets for Identical Assets |  |  | Significant Other Observable Inputs |  |  | Significant Unobservable Inputs |
|  | Total |  |  | Level 1 |  |  | Level 2 |  |  | Level 3 |
Assets: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Cash and cash equivalents |  | $ | 90,434,435 |  |  | $ | 90,434,435 |  |  | $ | — |  |  | $ | — |
Money market funds |  |  | 26,046,974 |  |  |  | 26,046,974 |  |  |  | — |  |  |  | — |
Restricted cash |  |  | 404,850 |  |  |  | 404,850 |  |  |  | — |  |  |  | — |
Total Assets |  | $ | 116,886,259 |  |  | $ | 116,886,259 |  |  | $ | — |  |  | $ | — |
|  | Fair Value Measurements at December 31, 2012 |
|  |  |  |  | Quoted Prices in Active Markets for Identical Assets |  |  | Significant Other Observable Inputs |  |  | Significant Unobservable Inputs |
|  | Total |  |  | Level 1 |  |  | Level 2 |  |  | Level 3 |
Assets: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Cash and cash equivalents |  | $ | 18,695,197 |  |  | $ | 18,695,197 |  |  | $ | — |  |  | $ | — |
Money market funds |  |  | 29,047,958 |  |  |  | 29,047,958 |  |  |  | — |  |  |  | — |
Restricted cash |  |  | 404,850 |  |  |  | 404,850 |  |  |  | — |  |  |  | — |
Total Assets |  | $ | 48,148,005 |  |  | $ | 48,148,005 |  |  | $ | — |  |  | $ | — |
Liabilities: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Preferred stock warrant liability |  | $ | (52,947 | ) |  | $ | — |  |  | $ | — |  |  | $ | (52,947 | )
Summary of Preferred Stock Warrant Liability | The following table provides a rollforward of the Company’s preferred stock warrant liability, which was the only financial instrument measured at fair value on a recurring basis using significant unobservable inputs (Level 3) as defined in ASC 820:
Balance at December 31, 2012 |  | $ | (52,947 | )
Total unrealized gains (losses) included in earnings |  |  | (626,349 | )
Settlement of preferred stock warrants |  |  | 679,296 |
Balance at December 31, 2013 |  | $ | — |
Estimated Useful Lives | Repairs and maintenance costs are expensed as incurred. Depreciation is computed using the straight-line method over the following estimated useful lives:
Computer equipment |  | 3 years
Software |  | 3 years
Furniture |  | 10 years
Laboratory and office equipment |  | 5 years
Leasehold improvements |  | Shorter of lease term or useful life
Computation of Basic and Diluted Income (Loss) Per Common Share | Basic and diluted income (loss) per common share is computed as follows:
|  | Year Ended December 31, |
|  | 2013 |  |  | 2012 |  |  | 2011 |
Net income (loss) |  | $ | (260,835 | ) |  | $ | 8,361,755 |  |  | $ | 6,717,120 |
Less: undistributed earnings allocated to participating securities |  |  | — |  |  |  | (8,361,755 | ) |  |  | (6,717,120 | )
Net income (loss) allocable to common shares |  | $ | (260,835 | ) |  | $ | — |  |  | $ | — |
Basic weighted average common shares outstanding |  |  | 6,847,697 |  |  |  | 1,083,276 |  |  |  | 1,025,602 |
Basic income (loss) per common share |  | $ | (0.04 | ) |  | $ | 0.00 |  |  | $ | 0.00 |
Net income (loss) |  | $ | (260,835 | ) |  | $ | 8,361,755 |  |  | $ | 6,717,120 |
Less: undistributed earnings allocated to participating securities and other add-backs to net income (loss) |  |  | — |  |  |  | (8,361,755 | ) |  |  | (6,717,120 | )
Net income (loss) allocable to common shares |  | $ | (260,835 | ) |  | $ | — |  |  | $ | — |
Basic weighted average common shares outstanding |  |  | 6,847,697 |  |  |  | 1,083,276 |  |  |  | 1,025,602 |
Effect of dilutive securities |  |  | — |  |  |  | — |  |  |  | — |
Diluted weighted average common shares outstanding |  |  | 6,847,697 |  |  |  | 1,083,276 |  |  |  | 1,025,602 |
Diluted income (loss) per common share |  | $ | (0.04 | ) |  | $ | 0.00 |  |  | $ | 0.00 |
Schedule of Dilutive Securities Used In Calculation of Diluted Earnings Per Share | The following common stock equivalents were excluded from the calculation of diluted net income (loss) per share because their effect would be anti-dilutive:
|  | Year Ended December 31, |
|  | 2013 |  |  | 2012 |  |  | 2011 |
Series A-1 Preferred Stock |  |  | — |  |  |  | 2,156,114 |  |  |  | 2,156,114 |
Series A-2 Preferred Stock |  |  | — |  |  |  | 392,274 |  |  |  | 392,274 |
Series B Preferred Stock |  |  | — |  |  |  | 4,336,037 |  |  |  | 4,336,037 |
Series C Preferred Stock |  |  | — |  |  |  | 5,909,906 |  |  |  | 5,909,906 |
Series D Preferred Stock |  |  | — |  |  |  | 769,468 |  |  |  | 769,468 |
Series D-2 Preferred Stock |  |  | — |  |  |  | 3,391,991 |  |  |  | 3,391,991 |
Effect of Converted Preferred Stock |  |  | 13,189,920 |  |  |  | — |  |  |  | — |
Warrants to purchase Series D-2 Preferred Stock |  |  | — |  |  |  | 180,784 |  |  |  | 180,784 |
Stock Options |  |  | 2,313,970 |  |  |  | 3,249,702 |  |  |  | 2,885,417 |
Summary of Significant Revenue [Member] |
Summary of Percentage of Customer Concentration | The following table represents the percentage of all significant revenue earned in the periods indicated:
|  | Year Ended December 31, |
|  | 2013 |  |  | 2012 |  |  | 2011 |
Servier |  |  | 51.6 | % |  |  | 17.3 | % |  |  | — |
Boehringer |  |  | 24.8 | % |  |  | 18.4 | % |  |  | 15.6 | %
Gilead |  |  | 13.8 | % |  |  | — |  |  |  | — |
Pfizer |  |  | 6.0 | % |  |  | 8.7 | % |  |  | 10.8 | %
Government Agencies |  |  | 2.2 | % |  |  | 6.5 | % |  |  | 17.7 | %
Eli Lilly |  |  | 1.4 | % |  |  | 48.9 | % |  |  | 54.0 | %
Summary of Significant Accounts Receivable[Member] |
Summary of Percentage of Customer Concentration | The following table represents the percentage of all significant accounts receivable:
|  | December 31, |
|  | 2013 |  |  | 2012 |
Gilead |  |  | 53.4 | % |  |  | — |
Pfizer. |  |  | 12.3 | % |  |  | 45.4 | %
Boehringer |  |  | 12.2 | % |  |  | 18.0 | %
Eli Lilly |  |  | 7.0 | % |  |  | 28.2 | %
Servier |  |  | 6.4 | % |  |  | — |
Government Agencies |  |  | 4.6 | % |  |  | 8.4 | %

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