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Subsequent Events - Additional Information (Detail) (Subsequent Event [Member], USD $)
In Millions, except Share data, unless otherwise specified
 1 Months Ended
Feb. 28, 2014
Subsequent Event [Line Items]  
Clinical milestone payments $ 5.0
Additional license grant fees 15.0
Review period 30 days
Common stock number of shares sold 1,800,000
Common stock, price per share $ 36.50
Additional shares sold under over-allotments Option to underwriter 450,000
Additional shares sold under over-allotments option to underwriter, price per share $ 36.50
Proceeds from sale of shares 76.7
Servier [Member]
  
Subsequent Event [Line Items]  
Clinical milestone payments 5.0
Additional license grant fees $ 15.0
Review period 30 days