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Commitments and Contingencies - Additional Information (Detail)
 9 Months Ended
Sep. 30, 2014
Operating Leased Assets [Line Items]  
Lessee leasing arrangements, operating leases, renewal term 5 years
Manufacturing Facility [Member]
  
Operating Leased Assets [Line Items]  
Amended lease expiration date Dec. 31, 2019
Term of additional space lease 4 years
Origination date for additional space in manufacturing facility Apr. 01, 2014
Lease [Member] | Office and Laboratory Space [Member]
  
Operating Leased Assets [Line Items]  
Lease expiration date Mar. 31, 2018
Lease [Member] | Manufacturing Facility [Member]
  
Operating Leased Assets [Line Items]  
Lease expiration date Dec. 31, 2014
Sublease [Member] | Office and Laboratory Space [Member]
  
Operating Leased Assets [Line Items]  
Lease expiration date Dec. 31, 2018
Subsequent Event [Member]
  
Operating Leased Assets [Line Items]  
Term of additional space lease 5 years
Origination date for additional space in manufacturing facility Feb. 01, 2015
Lease agreement description Subsequent to September 30, 2014, the Company entered into a five year lease agreement for additional office space effective February 1, 2015. The Company also amended its office and laboratory space lease originally expiring on March 31, 2018 to be co-terminus with the new lease.