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Consolidated Statements of Operations and Comprehensive Income (Loss) (USD $) | 9 Months Ended | 12 Months Ended
--- | --- | ---
Sep. 30, 2013 | Sep. 30, 2012 | Dec. 31, 2012 | Dec. 31, 2011
Revenues: |  |  |  |
Revenue from collaborative research | $ 42,015,994 | $ 50,283,510 | $ 59,645,819 | $ 47,054,397
Grant revenue | 1,112,238 | 3,744,047 | 4,180,279 | 10,152,969
Total revenues | 43,128,232 | 54,027,557 | 63,826,098 | 57,207,366
Costs and expenses: |  |  |  |
Research and development | 32,233,828 | 36,924,987 | 45,432,894 | 41,088,899
General and administrative | 7,322,974 | 6,640,740 | 10,187,894 | 10,868,791
Total costs and expenses | 39,556,802 | 43,565,727 | 55,620,788 | 51,957,690
Income (loss) from operations | 3,571,430 | 10,461,830 | 8,205,310 | 5,249,676
Other income (expense) | (627,281) | 4,752 | 156,445 | 1,467,444
Net comprehensive income (loss) | $ 2,944,149 | $ 10,466,582 | $ 8,361,755 | $ 6,717,120
Basic net income (loss) per common share | $ 0.00 | $ 0.00 | $ 0.00 | $ 0.00
Diluted net income (loss) per common share | $ 0.00 | $ 0.00 | $ 0.00 | $ 0.00
Basic weighted average number of common shares | 1,463,798 | 1,078,145 | 1,083,286 | 1,025,602
Diluted weighted average number of common shares | 21,908,859 | 21,412,848 | 1,083,286 | 1,025,602
Pro forma basic net income (loss) per common share | $ 0.16 |  | $ 0.38 |
Pro forma diluted net income (loss) per common share | $ 0.14 |  | $ 0.38 |
Pro forma basic weighted average number of common shares | 18,419,588 |  | 18,039,142 |
Pro forma diluted weighted average number of common shares | 20,328,791 |  | 21,473,689 |

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