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Subsequent Events - Additional Information (Detail) (USD $)
In Millions, except Share data, unless otherwise specified
 1 Months Ended
Sep. 30, 2013
Dec. 31, 2012
Dec. 31, 2011
Oct. 16, 2013
Subsequent Event [Member]
Feb. 07, 2014
Subsequent Event [Member]
Servier [Member]
Second Right to Develop Collaboration [Member]
Oct. 31, 2013
Subsequent Event [Member]
IPO [Member]
Oct. 16, 2013
Subsequent Event [Member]
IPO [Member]
Subsequent Event [Line Items]              
Initial public offering number of share sold           5,000,000  
Initial public offering price per share             $ 16.00
Additional shares sold under over-allotments Option to underwriter           750,000  
Proceeds from initial public offering net of expenses           $ 83.8  
Common stock, shares issued 2,124,624 1,098,914 1,049,030 25,020,288      
Common stock, shares outstanding 2,124,624 1,098,914 1,049,030 25,020,288      
Preferred stock, shares outstanding       0      
Milestone Payments Triggered 5.0            
Research Maintenance Payment 4.0            
License grant fees earned         15    
Clinical milestone payments earned         $ 5