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Consolidated Statements of Cash Flows (USD $)
In Thousands, unless otherwise specified
 12 Months Ended
Dec. 31, 2014
Dec. 31, 2013
Dec. 31, 2012
Operating activities      
Net income (loss) $ (38,313)us-gaap_NetIncomeLoss $ (261)us-gaap_NetIncomeLoss $ 8,362us-gaap_NetIncomeLoss
Adjustments to reconcile net income (loss) to net cash used in operating activities:      
Depreciation expense 1,822us-gaap_Depreciation 1,193us-gaap_Depreciation 960us-gaap_Depreciation
Share-based compensation 3,244us-gaap_ShareBasedCompensation 862us-gaap_ShareBasedCompensation 838us-gaap_ShareBasedCompensation
Fair value adjustment of warrant liability   626us-gaap_FairValueAdjustmentOfWarrants (151)us-gaap_FairValueAdjustmentOfWarrants
Changes in operating assets and liabilities:      
Accounts receivable (931)us-gaap_IncreaseDecreaseInAccountsReceivable 42us-gaap_IncreaseDecreaseInAccountsReceivable 1,352us-gaap_IncreaseDecreaseInAccountsReceivable
Prepaid expenses (3,239)us-gaap_IncreaseDecreaseInPrepaidExpense (834)us-gaap_IncreaseDecreaseInPrepaidExpense (91)us-gaap_IncreaseDecreaseInPrepaidExpense
Restricted cash 105us-gaap_IncreaseDecreaseInRestrictedCashForOperatingActivities   177us-gaap_IncreaseDecreaseInRestrictedCashForOperatingActivities
Other assets (1,179)us-gaap_IncreaseDecreaseInOtherOperatingAssets (375)us-gaap_IncreaseDecreaseInOtherOperatingAssets 1us-gaap_IncreaseDecreaseInOtherOperatingAssets
Accounts payable (1,500)us-gaap_IncreaseDecreaseInAccountsPayable (570)us-gaap_IncreaseDecreaseInAccountsPayable (7,312)us-gaap_IncreaseDecreaseInAccountsPayable
Accrued expenses 4,346us-gaap_IncreaseDecreaseInAccruedLiabilities 2,347us-gaap_IncreaseDecreaseInAccruedLiabilities 185us-gaap_IncreaseDecreaseInAccruedLiabilities
Lease exit liability (1,439)us-gaap_IncreaseDecreaseInRestructuringReserve (629)us-gaap_IncreaseDecreaseInRestructuringReserve (534)us-gaap_IncreaseDecreaseInRestructuringReserve
Deferred revenue 3,317us-gaap_IncreaseDecreaseInDeferredRevenue (16,676)us-gaap_IncreaseDecreaseInDeferredRevenue (10,810)us-gaap_IncreaseDecreaseInDeferredRevenue
Deferred rent (234)mgnx_IncreaseDecreaseInDeferredRent 103mgnx_IncreaseDecreaseInDeferredRent 441mgnx_IncreaseDecreaseInDeferredRent
Other liabilities 1,242us-gaap_IncreaseDecreaseInOtherCurrentLiabilities    
Net cash used in operating activities (32,759)us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations (14,172)us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations (6,582)us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations
Cash flows from investing activities      
Purchases of property and equipment (3,572)us-gaap_PaymentsToAcquirePropertyPlantAndEquipment (2,961)us-gaap_PaymentsToAcquirePropertyPlantAndEquipment (940)us-gaap_PaymentsToAcquirePropertyPlantAndEquipment
Net cash used in investing activities (3,572)us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperations (2,961)us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperations (940)us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperations
Cash flows from financing activities      
Proceeds from issuance of common stock, net of offering costs 76,716us-gaap_ProceedsFromIssuanceOfCommonStock 84,771us-gaap_ProceedsFromIssuanceOfCommonStock  
Proceeds from stock option exercises 744us-gaap_ProceedsFromStockOptionsExercised 1,100us-gaap_ProceedsFromStockOptionsExercised 47us-gaap_ProceedsFromStockOptionsExercised
Purchase of treasury stock (19)us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation    
Net cash provided by financing activities 77,441us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperations 85,871us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperations 47us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperations
Net change in cash and cash equivalents 41,110us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease 68,738us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease (7,475)us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease
Cash and cash equivalents at beginning of period 116,481us-gaap_CashAndCashEquivalentsAtCarryingValue 47,743us-gaap_CashAndCashEquivalentsAtCarryingValue 55,218us-gaap_CashAndCashEquivalentsAtCarryingValue
Cash and cash equivalents at end of period 157,591us-gaap_CashAndCashEquivalentsAtCarryingValue 116,481us-gaap_CashAndCashEquivalentsAtCarryingValue 47,743us-gaap_CashAndCashEquivalentsAtCarryingValue
Noncash financing activities:      
Conversion of preferred stock   $ 2,947us-gaap_ConversionOfStockAmountConverted1