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CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE INCOME (LOSS) (USD $)
In Thousands, except Share data, unless otherwise specified
 3 Months Ended
Mar. 31, 2015
Mar. 31, 2014
Revenues:    
Revenue from collaborative research $ 71,165us-gaap_LicenseAndServicesRevenue $ 14,401us-gaap_LicenseAndServicesRevenue
Grant revenue 114us-gaap_RevenueFromGrants 318us-gaap_RevenueFromGrants
Total revenues 71,279us-gaap_Revenues 14,719us-gaap_Revenues
Costs and expenses:    
Research and development 21,464us-gaap_ResearchAndDevelopmentExpense 14,569us-gaap_ResearchAndDevelopmentExpense
General and administrative 4,683us-gaap_GeneralAndAdministrativeExpense 3,258us-gaap_GeneralAndAdministrativeExpense
Total costs and expenses 26,147us-gaap_CostsAndExpenses 17,827us-gaap_CostsAndExpenses
Income (loss) from operations 45,132us-gaap_OperatingIncomeLoss (3,108)us-gaap_OperatingIncomeLoss
Other income (expense) (3)us-gaap_OtherNonoperatingIncomeExpense 0us-gaap_OtherNonoperatingIncomeExpense
Net comprehensive income (loss) $ 45,129us-gaap_NetIncomeLoss $ (3,108)us-gaap_NetIncomeLoss
Basic net income (loss) per common share (in dollars per share) $ 1.53us-gaap_EarningsPerShareBasic $ (0.12)us-gaap_EarningsPerShareBasic
Diluted net income (loss) per common share (in dollars per share) $ 1.42us-gaap_EarningsPerShareDiluted $ (0.12)us-gaap_EarningsPerShareDiluted
Weighted average shares outstanding, basic 29,415,768us-gaap_WeightedAverageNumberOfSharesOutstandingBasic 26,262,356us-gaap_WeightedAverageNumberOfSharesOutstandingBasic
Diluted weighted average common shares outstanding (in shares) 31,684,174us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding 26,262,356us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding