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CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE INCOME (LOSS) - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2015
Jun. 30, 2014
Jun. 30, 2015
Jun. 30, 2014
Revenues:        
Revenue from collaborative research $ 5,598 $ 9,202 $ 76,763 $ 23,603
Grant revenue 1,118 18 1,232 336
Total revenues 6,716 9,220 77,995 23,939
Costs and expenses:        
Research and development 22,660 17,335 44,124 31,904
General and administrative 5,346 4,145 10,029 7,403
Total costs and expenses 28,006 21,480 54,153 39,307
Income (loss) from operations (21,290) (12,260) 23,842 (15,368)
Other income (expense) (86) 1 (89) 1
Net comprehensive income (loss) $ (21,376) $ (12,259) $ 23,753 $ (15,367)
Basic net income (loss) per common share (in dollars per share) $ (0.71) $ (0.44) $ 0.80 $ (0.57)
Diluted net income (loss) per common share (in dollars per share) $ (0.71) $ (0.44) $ 0.75 $ (0.57)
Weighted average shares outstanding, basic 30,059,329 27,651,297 29,739,326 26,960,664
Diluted weighted average common shares outstanding (in shares) 30,059,329 27,651,297 31,797,332 26,960,664