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Collaboration and Other Agreements, Janssen Biotech, Inc. (Details) - Janssen Biotech Inc. [Member] $ / shares in Units, $ in Millions | 12 Months Ended
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Dec. 31, 2015 USD ($) $ / shares shares
Collaboration and Other Agreements [Line Items] |
Collaboration agreement date | December 2014
Sale of common stock (in shares) | shares | 1,923,077
Sale of common stock (in dollars per share) | $ / shares | $ 39.00
Proceeds of stock sale | $ 75.0
Premium received on stock purchase | 12.3
Non-refundable upfront payment receivable | 50.0
Total consideration | 125.0
Amount allocated to equity | 62.7
Amount allocated to license and R&D | 62.3
Clinical milestone earned during period | 10.0
Recognized revenue under agreement | 72.3
Maximum [Member] |
Collaboration and Other Agreements [Line Items] |
Potential Clinical Milestone Payments Under Agreement | 205.0
Potential Sales Milestone Payments Under Agreement | 150.0
Potential Regulatory Milestone Payments Under Agreement | $ 220.0

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