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Lease Exit Liability - Future Principal Payments Under Lease Agreement (Details) - USD ($) | 12 Months Ended |
--- | --- | ---
Dec. 31, 2015 | Dec. 31, 2014 | Dec. 31, 2013 | Jul. 16, 2008
Operating Leased Assets [Line Items] |  |  |  |
2016 | $ 6,130,000 |  |  |
2017 | 6,314,000 |  |  |
2018 | 4,210,000 |  |  |
Total | $ 27,809,000 |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |
Operating Lease | 2018 |  |  |
Onetime purchase payment under purchase agreement |  |  |  | $ 5,000,000
Additional amounts recorded | $ 0 | $ 0 | $ 0 |
Minimum [Member] |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |
Onetime payment paid under license of product |  |  |  | 8,000,000
Maximum [Member] |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |
Onetime payment paid under license of product |  |  |  | $ 12,000,000
Raven Biotechnologies Inc. [Member] |  |  |  |
Operating Leased Assets [Line Items] |  |  |  |
2016 | 2,020,000 |  |  |
2017 | 2,281,000 |  |  |
2018 | 412,000 |  |  |
Total | $ 4,713,000 |  |  |

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