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v3.3.1.900

Commitments and Contingencies (Details) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2015 USD ($) Lease | Dec. 31, 2014 USD ($) | Dec. 31, 2013 USD ($)
Minimum [Member] |  |  |
Operating Leased Assets [Line Items] |  |  |
Lease expiration date | Apr. 30, 2018 |  |
Maximum [Member] |  |  |
Operating Leased Assets [Line Items] |  |  |
Lease expiration date | Dec. 31, 2022 |  |
Number of leases | Lease | 5 |  |
Deferred rent liability | $ 7,300 | $ 2,700 |
Rent expense | 900 | $ 2,000 | $ 2,700
Lease incentives | 5,100 |  |
Future minimum rental payments required under all non-cancelable operating leases [Abstract] |  |  |
2016 | 6,130 |  |
2017 | 6,314 |  |
2018 | 4,210 |  |
2019 | 3,803 |  |
2020 | 2,142 |  |
Thereafter | 5,210 |  |
Total | $ 27,809 |  |
Office and Laboratory Space [Member] | South San Francisco [Member] |  |  |
Operating Leased Assets [Line Items] |  |  |
Lease expiration date | Feb. 28, 2018 |  |
Office, Laboratory and Manufacturing Space [Member] |  |  |
Operating Leased Assets [Line Items] |  |  |
Lessee leasing arrangements, term of operating leases | 7 years |  |
Lessee leasing arrangements, origination date | Jul. 31, 2015 |  |
Lease Commencement Date | Jan. 01, 2016 |  |

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- Definition The cumulative difference between the rental payments required by a lease agreement and the rental income or expense recognized on a straight-line basis, or other systematic and rational basis more representative of the time pattern in which use or benefit is granted or derived from the leased property, expected to be recognized in income or expense over the term of the leased property by the lessor or lessee, respectively. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 840 -SubTopic 20 -Section 25 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=7501430&loc=d3e39896-112707 + Details
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- Definition Amount of required minimum rental payments for leases having an initial or remaining non-cancelable letter-terms in excess of one year. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 840 -SubTopic 10 -Section 55 -Paragraph 40 -Subparagraph (Note 3) -URI http://asc.fasb.org/extlink&oid=6584154&loc=d3e38371-112697 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 840 -SubTopic 20 -Section 50 -Paragraph 2 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=6453985&loc=d3e41502-112717 + Details
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- Definition Amount of required minimum rental payments for operating leases having an initial or remaining non-cancelable lease term in excess of one year due in the next fiscal year following the latest fiscal year. Excludes interim and annual periods when interim periods are reported on a rolling approach, from latest balance sheet date. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 840 -SubTopic 10 -Section 55 -Paragraph 40 -Subparagraph (Note 3) -URI http://asc.fasb.org/extlink&oid=6584154&loc=d3e38371-112697 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 840 -SubTopic 20 -Section 50 -Paragraph 2 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=6453985&loc=d3e41502-112717 + Details
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