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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Operating activities      
Net loss $ (20,140) $ (38,313) $ (261)
Adjustments to reconcile net loss to net cash used in operating activities:      
Depreciation expense 2,863 1,822 1,193
Share-based compensation 7,847 3,244 862
Fair value adjustment of warrant liability 0 0 626
Changes in operating assets and liabilities:      
Accounts receivable 1,711 (931) 42
Prepaid expenses 2,405 (3,239) (834)
Restricted cash 300 105 0
Other assets (285) (1,179) (375)
Accounts payable (163) (1,500) (570)
Accrued expenses 3,545 4,346 2,347
Lease exit liability (3,293) (1,439) (629)
Deferred revenue (12,223) 3,317 (16,676)
Deferred rent 4,650 (234) 103
Other liabilities (878) 1,242 0
Net cash used in operating activities (13,661) (32,759) (14,172)
Cash flows from investing activities      
Purchases of marketable securities (142,910) 0 0
Purchases of property and equipment (9,197) (3,572) (2,961)
Net cash used in investing activities (152,107) (3,572) (2,961)
Cash flows from financing activities      
Proceeds from issuance of common stock, net of offering costs 203,467 76,716 84,771
Proceeds from stock option exercises 911 744 1,100
Purchase of treasury stock (29) (19) 0
Net cash provided by financing activities 204,349 77,441 85,871
Net change in cash and cash equivalents 38,581 41,110 68,738
Cash and cash equivalents at beginning of period 157,591 116,481 47,743
Cash and cash equivalents at end of period 196,172 157,591 116,481
Noncash financing activities:      
Conversion of preferred stock $ 0 $ 0 $ 2,947