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Summary of Significant Accounting Policies - Summary of Fair Value Measurement Financial Asset and Liabilities (Details) - USD ($)
$ in Thousands
Dec. 31, 2016
Dec. 31, 2015
Assets [Abstract]    
Cash and cash equivalents $ 50,800 $ 108,000
Total assets measured at fair value 251,666 250,831
Money market funds    
Assets [Abstract]    
Cash and cash equivalents 46,781 62,353
U.S Treasury securities    
Assets [Abstract]    
Marketable securities 8,826 9,348
Government-sponsored enterprises    
Assets [Abstract]    
Marketable securities 29,759 41,202
Corporate debt securities    
Assets [Abstract]    
Marketable securities 166,300 137,928
Quoted Prices in Active Markets for Identical Assets, Level 1    
Assets [Abstract]    
Total assets measured at fair value 46,781 62,353
Quoted Prices in Active Markets for Identical Assets, Level 1 | Money market funds    
Assets [Abstract]    
Cash and cash equivalents 46,781 62,353
Quoted Prices in Active Markets for Identical Assets, Level 1 | U.S Treasury securities    
Assets [Abstract]    
Marketable securities 0 0
Quoted Prices in Active Markets for Identical Assets, Level 1 | Government-sponsored enterprises    
Assets [Abstract]    
Marketable securities 0 0
Quoted Prices in Active Markets for Identical Assets, Level 1 | Corporate debt securities    
Assets [Abstract]    
Marketable securities 0 0
Significant Other Observable Inputs, Level 2    
Assets [Abstract]    
Total assets measured at fair value 204,885 188,478
Significant Other Observable Inputs, Level 2 | Money market funds    
Assets [Abstract]    
Cash and cash equivalents 0 0
Significant Other Observable Inputs, Level 2 | U.S Treasury securities    
Assets [Abstract]    
Marketable securities 8,826 9,348
Significant Other Observable Inputs, Level 2 | Government-sponsored enterprises    
Assets [Abstract]    
Marketable securities 29,759 41,202
Significant Other Observable Inputs, Level 2 | Corporate debt securities    
Assets [Abstract]    
Marketable securities 166,300 137,928
Significant Unobservable Inputs, Level 3    
Assets [Abstract]    
Total assets measured at fair value 0 0
Significant Unobservable Inputs, Level 3 | Money market funds    
Assets [Abstract]    
Cash and cash equivalents 0 0
Significant Unobservable Inputs, Level 3 | U.S Treasury securities    
Assets [Abstract]    
Marketable securities 0 0
Significant Unobservable Inputs, Level 3 | Government-sponsored enterprises    
Assets [Abstract]    
Marketable securities 0 0
Significant Unobservable Inputs, Level 3 | Corporate debt securities    
Assets [Abstract]    
Marketable securities $ 0 $ 0