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Collaboration and Other Agreements - Janssen Biotech, Inc. (Details) - Janssen Biotech, Inc. - USD ($)
1 Months Ended 3 Months Ended 6 Months Ended
Jul. 31, 2016
Jan. 31, 2015
Jun. 30, 2017
Jun. 30, 2016
Jun. 30, 2017
Jun. 30, 2016
Janssen MGD011 Agreement            
Collaboration and Other Agreements [Line Items]            
Sale of common stock (in shares)   1,923,077        
Proceeds of stock sale   $ 75,000,000        
Non-refundable upfront payment   $ 50,000,000        
Revenue recognized under agreement     $ 0 $ 0 $ 0 $ 0
Sale of common stock (in dollars per share)   $ 39.00        
Premium received on stock purchase   $ 12,300,000        
Total consideration   125,000,000        
Amount allocated to equity   62,700,000        
Amount allocated to license and R&D   $ 62,300,000        
Janssen MGD011 Agreement | Maximum            
Collaboration and Other Agreements [Line Items]            
Potential clinical milestone payments     205,000,000.0   205,000,000.0  
Potential regulatory milestone payments under agreement     220,000,000.0   220,000,000.0  
Potential sales milestone payments under agreement     150,000,000.0   150,000,000.0  
Janssen MGD015 Agreement            
Collaboration and Other Agreements [Line Items]            
Non-refundable upfront payment $ 75,000,000          
Revenue recognized under agreement     200,000 $ 0 300,000 $ 0
Janssen MGD015 Agreement | Maximum            
Collaboration and Other Agreements [Line Items]            
Potential clinical milestone payments     100,000,000.0   100,000,000.0  
Potential regulatory milestone payments under agreement     265,000,000.0   265,000,000.0  
Potential sales milestone payments under agreement     $ 300,000,000.0   $ 300,000,000.0