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Collaboration and Other Agreements - Janssen Biotech, Inc. (Details) - Janssen Biotech, Inc. - USD ($)
1 Months Ended 3 Months Ended 9 Months Ended
May 31, 2016
Dec. 31, 2014
Sep. 30, 2017
Sep. 30, 2016
Sep. 30, 2017
Sep. 30, 2016
Janssen MGD011 Agreement            
Collaboration and Other Agreements [Line Items]            
Sale of common stock (in shares)   1,923,077        
Proceeds of stock sale   $ 75,000,000        
Non-refundable upfront payment   $ 50,000,000        
Janssen MGD015 Agreement            
Collaboration and Other Agreements [Line Items]            
Non-refundable upfront payment $ 75,000,000          
Revenue recognized under agreement     $ 200,000 $ 0 $ 500,000 $ 75,000,000
Janssen MGD015 Agreement | Maximum            
Collaboration and Other Agreements [Line Items]            
Potential clinical milestone payments     100,000,000.0   100,000,000.0  
Potential regulatory milestone payments under agreement     265,000,000.0   265,000,000.0  
Potential sales milestone payments under agreement     $ 300,000,000.0   $ 300,000,000.0