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Stock-Based Compensation - Stock Option Activity (Details) - USD ($)
$ / shares in Units, $ in Thousands
9 Months Ended 12 Months Ended
Sep. 30, 2017
Dec. 31, 2016
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding [Roll Forward]    
Shares, Outstanding, Beginning Balance (in shares) 3,838,060  
Shares, Granted (in shares) 1,219,725  
Shares, Exercised (in shares) (219,732)  
Shares, Forfeited or expired (in shares) (304,259)  
Shares, Outstanding, Ending Balance (in shares) 4,533,794 3,838,060
Shares, Exercisable (in shares) 2,704,057  
Shares, Vested and expected to vest (in shares) 4,352,976  
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract]    
Weighted- Average Exercise Price, Outstanding, Beginning Balance (in dollars per share) $ 18.93  
Weighted- Average Exercise Price, Granted (in dollars per share) 20.09  
Weighted- Average Exercise Price, Exercised (in dollars per share) 2.02  
Weighted- Average Exercise Price, Forfeited or expired (in dollars per share) 24.13  
Weighted- Average Exercise Price, Outstanding, Ending Balance (in dollars per share) 19.71 $ 18.93
Weighted- Average Exercise Price, Exercisable (in dollars per share) 16.86  
Weighted- Average Exercise Price, Vested and expected to vest (in dollars per share) $ 19.48  
Share-based Compensation Arrangement by Share-based Payment Award, Options, Additional Disclosures [Abstract]    
Weighted- Average Remaining Contractual Term, Outstanding 7 years 2 months 19 days 7 years
Weighted- Average Remaining Contractual Term, Exercisable 6 years 2 months 12 days  
Weighted- Average Remaining Contractual Term, Vested and expected to vest 7 years 2 months 12 days  
Aggregate Intrinsic Value, Outstanding, Ending Balance $ 18,050  
Aggregate Intrinsic Value, Exercisable 17,254  
Aggregate Intrinsic Value, Vested and expected to vest $ 17,993  
Weighted-average grant-date fair value of options granted (in dollars per share) $ 12.56  
Intrinsic value of options exercised $ 3,700  
Cash received for options exercised 400  
Fair value of shares vested 10,700  
Unrecognized compensation expense related to non-vested stock-options, net of related forfeiture estimates $ 23,700  
Unrecognized compensation expense recognition period 2 years 6 months