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Lease Exit Liability Lease Exit Liability - Narrative (Details) - USD ($)
$ in Millions
 12 Months Ended
Dec. 31, 2017
Dec. 31, 2015
Jul. 06, 2017
May 31, 2016
Restructuring Cost and Reserve [Line Items]        
Future sublease payments to be received $ 0.1   $ 2.4  
Reduction in research and development expense $ 1.3      
Reduction of research and development expense   $ 1.9    
Raven Biotechnologies Inc.        
Restructuring Cost and Reserve [Line Items]        
Future sublease payments to be received       $ 1.3