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Collaboration and Other Agreements, NIAID Contract (Details) - NIAID
12 Months Ended
Sep. 15, 2015
USD ($)
Molecule
Dec. 31, 2017
USD ($)
Dec. 31, 2016
USD ($)
Dec. 31, 2015
USD ($)
Collaboration and Other Agreements [Line Items]        
Commercialization of molecules | Molecule 2      
Base period value $ 7,500,000      
Proceeds from additional development funding options under agreement   $ 10,800,000    
Recognized revenue under agreement   $ 1,700,000 $ 5,100,000 $ 200,000
Maximum        
Collaboration and Other Agreements [Line Items]        
Additional development funding options 17,000,000.0      
Total potential value $ 24,500,000.0