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Basis of Presentation and Significant Accounting Policies (Tables)
 3 Months Ended
Mar. 31, 2018
Organization, Consolidation and Presentation of Financial Statements [Abstract]  
Schedule of Effect of New Accounting Pronouncement
As a result of applying the modified retrospective method to adopt the new guidance, the following adjustments were made to accounts on the consolidated balance sheet as of January 1, 2018 (in thousands):
 
 
Pre-Adoption
 
ASC 606 Adjustment
 
Post-Adoption
Deferred revenue, current
$
7,202

 
$
540

 
$
7,742

Deferred revenue, net of current portion
13,637

 
5,939

 
19,576

Accumulated deficit
(312,340
)
 
(6,479
)
 
(318,819
)

The transition adjustment resulted primarily from changes in the pattern of revenue recognition for upfront fees and the accounting for milestones.
The following table shows the impact of adoption to our consolidated statement of income and balance sheet (in thousands):
 
Three Months Ended March 31, 2018
As Reported
 
Balances without adoption of ASC 606
 
Effect of Change Higher/(Lower)
Revenue from collaborative agreements
$
4,501

 
$
4,366

 
$
135

Net loss
(49,536
)
 
(49,671
)
 
(135
)
Basic and diluted net loss per common share
$
(1.34
)
 
$
(1.35
)
 
$
0.01

 
 
 
 
 
 
 
 
As of March 31, 2018
As Reported
 
Balances without adoption of ASC 606
 
Effect of Change Higher/(Lower)
Deferred revenue, current
$
8,121

 
$
7,417

 
$
704

Deferred revenue, net of current portion
17,762

 
12,122

 
5,640

Accumulated deficit
(368,355
)
 
(362,011
)
 
6,344
Schedule of Changes in Contract Liabilities
The following table presents changes in the Company’s contract liabilities during the three months ended March 31, 2018 (in thousands):
 
 
Balance at Beginning of Period
 
Additions
 
Deductions
 
Balance at End of Period
   Deferred revenue
$
27,318

 
$
500

 
$
(1,935
)
 
$
25,883