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Stock-Based Compensation - Stock Option Activity (Details) - USD ($)
$ / shares in Units, $ in Thousands
9 Months Ended 12 Months Ended
Sep. 30, 2018
Dec. 31, 2017
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding [Roll Forward]    
Shares, Outstanding, Beginning Balance (in shares) 4,504,642  
Shares, Granted (in shares) 1,230,244  
Shares, Exercised (in shares) (205,902)  
Shares, Forfeited or expired (in shares) (180,709)  
Shares, Outstanding, Ending Balance (in shares) 5,348,275 4,504,642
Shares, Exercisable (in shares) 3,365,982  
Shares, Vested and expected to vest (in shares) 5,138,801  
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract]    
Weighted- Average Exercise Price, Outstanding, Beginning Balance (in dollars per share) $ 19.79  
Weighted- Average Exercise Price, Granted (in dollars per share) 27.43  
Weighted- Average Exercise Price, Exercised (in dollars per share) 5.47  
Weighted- Average Exercise Price, Forfeited or expired (in dollars per share) (24.25)  
Weighted- Average Exercise Price, Outstanding, Ending Balance (in dollars per share) 21.95 $ 19.79
Weighted- Average Exercise Price, Exercisable (in dollars per share) 19.70  
Weighted- Average Exercise Price, Vested and expected to vest (in dollars per share) $ 21.79  
Share-based Compensation Arrangement by Share-based Payment Award, Options, Additional Disclosures [Abstract]    
Weighted- Average Remaining Contractual Term, Outstanding 7 years 7 years
Weighted- Average Remaining Contractual Term, Exercisable 6 years  
Weighted- Average Remaining Contractual Term, Vested and expected to vest 7 years  
Aggregate Intrinsic Value, Outstanding, Ending Balance $ 19,762  
Aggregate Intrinsic Value, Exercisable 18,892  
Aggregate Intrinsic Value, Vested and expected to vest $ 19,671  
Weighted-average grant-date fair value of options granted (in dollars per share) $ 18.07  
Intrinsic value of options exercised $ 4,000  
Cash received for options exercised 900  
Fair value of shares vested 11,900  
Unrecognized compensation expense related to non-vested stock-options, net of related forfeiture estimates $ 28,000  
Unrecognized compensation expense recognition period 2 years 7 months 24 days