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Collaboration and Other Agreements, Servier (Details) - USD ($) | 1 Months Ended | 3 Months Ended | 12 Months Ended |  |
--- | --- | --- | --- | --- | ---
Sep. 30, 2012 | Dec. 31, 2018 | Sep. 30, 2018 | Jun. 30, 2018 | Mar. 31, 2018 | Dec. 31, 2017 | Sep. 30, 2017 | Jun. 30, 2017 | Mar. 31, 2017 | Dec. 31, 2018 | Dec. 31, 2017 | Dec. 31, 2016 | Jan. 01, 2018 | Dec. 31, 2015
Collaboration and Other Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Revenues |  | $ 15,794,000 | $ 20,798,000 | $ 18,834,000 | $ 4,695,000 | $ 152,359,000 | $ 1,663,000 | $ 1,666,000 | $ 2,055,000 | $ 60,121,000 | $ 157,742,000 | $ 91,880,000 |  |
Deferred revenue included in current liabilities |  | 21,721,000 |  |  |  | 7,202,000 |  |  |  | 21,721,000 | 7,202,000 |  | $ 7,742,000 |
Deferred revenue |  | 40,722,000 |  |  |  | 27,318,000 |  |  |  | 40,722,000 | 27,318,000 |  |  |
Increase in revenue recognized from ASC 606 adoption |  |  |  |  |  |  |  |  |  | 9,588,000 |  |  |  |
Servier | Servier DART |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaboration and Other Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Non-refundable upfront payment | $ 20,000,000.0 |  |  |  |  |  |  |  |  |  |  |  |  |
Milestone payment removed | 5,000,000.0 |  |  |  |  |  |  |  |  |  |  |  |  |
Option exercise fee |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 15,000,000.0
Offset to research and development costs under collaboration arrangement |  |  |  |  |  |  |  |  |  | 6,000,000.0 | 3,200,000 | 2,600,000 |  |
Deferred revenue |  | 12,600,000 |  |  |  |  |  |  |  | 12,600,000 |  |  |  |
Deferred revenue, current |  | 900,000 |  |  |  |  |  |  |  | 900,000 |  |  |  |
Deferred revenue, noncurrent |  | 11,700,000 |  |  |  |  |  |  |  | 11,700,000 |  |  |  |
Deferred revenue |  |  |  |  |  | 7,400,000 |  |  |  |  | 7,400,000 |  |  |
Increase in balance related to adoption of ASC 606 |  |  |  |  |  |  |  |  |  | 6,400,000 |  |  |  |
Increase in revenue recognized from ASC 606 adoption |  |  |  |  |  |  |  |  |  | 100,000 |  |  |  |
Servier | Maximum | Servier DART |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaboration and Other Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Potential clinical milestone payments under agreement | 22,500,000 |  |  |  |  |  |  |  |  |  |  |  |  |
Potential regulatory milestone payments under agreement | 76,000,000.0 |  |  |  |  |  |  |  |  |  |  |  |  |
Potential sales milestone payments under agreement | $ 210,000,000.0 |  |  |  |  |  |  |  |  |  |  |  |  |
Revenues From License Agreements | Servier | Servier DART |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaboration and Other Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Revenues |  |  |  |  |  |  |  |  |  | 1,200,000 | 1,400,000 | 2,200,000 |  |
Revenues From License Agreements | Servier | Servier Agreement - MGD007 Option |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaboration and Other Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Revenues |  |  |  |  |  |  |  |  |  | 1,900,000 | 1,100,000 | $ 1,100,000 |  |
Deferred revenue included in current liabilities |  |  |  |  |  | $ 1,100,000 |  |  |  |  | $ 1,100,000 |  |  |
Deferred revenue |  | $ 0 |  |  |  |  |  |  |  | $ 0 |  |  |  |

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