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Collaboration and Other Agreements, Incyte Corporation (Details) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended 12 Months Ended
Oct. 31, 2017
Dec. 31, 2018
Sep. 30, 2018
Jun. 30, 2018
Mar. 31, 2018
Dec. 31, 2017
Sep. 30, 2017
Jun. 30, 2017
Mar. 31, 2017
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
Collaboration and Other Agreements [Line Items]                        
Revenues   $ 15,794 $ 20,798 $ 18,834 $ 4,695 $ 152,359 $ 1,663 $ 1,666 $ 2,055 $ 60,121 $ 157,742 $ 91,880
Incyte MGA012 Agreement | Incyte Corporation (Incyte)                        
Collaboration and Other Agreements [Line Items]                        
Non-refundable upfront payment           $ 150,000            
Amounts recognized                   15,000    
Transaction price $ 154,000                      
Clinical trial activities selling price amount 4,000                      
Maximum | Incyte MGA012 Agreement | Incyte Corporation (Incyte)                        
Collaboration and Other Agreements [Line Items]                        
Potential development and regulatory milestone payments 420,000                      
Potential commercial milestone payments $ 330,000                      
Potential proceeds from royalties percent 24.00%                      
Minimum | Incyte MGA012 Agreement | Incyte Corporation (Incyte)                        
Collaboration and Other Agreements [Line Items]                        
Potential proceeds from royalties percent 15.00%                      
Revenues From License Agreements | Incyte MGA012 Agreement | Incyte Corporation (Incyte)                        
Collaboration and Other Agreements [Line Items]                        
Revenues                   18,800 $ 151,100  
Revenues From License Agreements | Incyte MGA012 Clinical Services | Incyte Corporation (Incyte)                        
Collaboration and Other Agreements [Line Items]                        
Revenues                   $ 22,200