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v3.19.1

CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY - USD ($) $ in Thousands | Total | Common Stock | Additional Paid-In Capital | Accumulated Deficit | Accumulated Other Comprehensive Income
--- | --- | --- | --- | --- | ---
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |
Cumulative effect of adoption of accounting standards | $ (6,479) |  |  |  |
Beginning balance (in shares) at Dec. 31, 2017 |  | 36,859,077 |  |  |
Beginning balance at Dec. 31, 2017 | 299,238 | $ 369 | $ 611,270 | $ (312,340) | $ (61)
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |
Share-based compensation | 3,386 |  | 3,386 |  |
Stock plan related activity | 629 | $ 1 | 628 |  |
Stock plan related activity (in shares) |  | 165,546 |  |  |
Unrealized gain on investments | 38 |  |  |  | 38
Net loss | (49,536) |  |  | (49,536) |
Ending balance (in shares) at Mar. 31, 2018 |  | 37,024,623 |  |  |
Ending balance at Mar. 31, 2018 | 247,276 | $ 370 | 615,284 | (368,355) | (23)
Beginning balance (in shares) at Dec. 31, 2018 |  | 42,353,301 |  |  |
Beginning balance at Dec. 31, 2018 | 242,877 | $ 424 | 732,727 | (490,271) | (3)
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |
Share-based compensation | 3,750 |  | 3,750 |  |
Issuance of common stock, net of offering costs (in shares) |  | 6,325,000 |  |  |
Issuance of common stock, net of offering costs | 118,657 | $ 63 | 118,594 |  |
Stock plan related activity | $ 347 | $ 1 | 346 |  |
Stock plan related activity (in shares) | 1,628,022 | 126,707 |  |  |
Unrealized gain on investments | $ 3 |  |  |  | 3
Net loss | (45,017) |  |  | (45,017) |
Ending balance (in shares) at Mar. 31, 2019 |  | 48,805,008 |  |  |
Ending balance at Mar. 31, 2019 | $ 320,617 | $ 488 | $ 855,417 | $ (535,288) | $ 0

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