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Stock-Based Compensation - Stock-Based Compensation Expense (Details) - USD ($) $ / shares in Units, $ in Thousands | 1 Months Ended | 3 Months Ended | 6 Months Ended | 9 Months Ended |
--- | --- | --- | --- | --- | ---
May 31, 2017 | Jun. 30, 2019 | Jun. 30, 2018 | Jun. 30, 2019 | Jun. 30, 2018 | Sep. 30, 2018 | Sep. 30, 2017 | Dec. 31, 2018
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |  |  |
Options outstanding (in shares) |  | 6,761,789 |  | 6,761,789 |  |  |  | 5,273,964
Weighted-average exercise price of stock options outstanding (in dollars per share) |  | $ 22.52 |  | $ 22.52 |  |  |  | $ 22.23
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items] |  |  |  |  |  |  |  |
Total stock-based compensation expense |  | $ 4,884 | $ 4,163 | $ 8,683 | $ 7,595 |  |  |
2016 Employee Stock Purchase Plan |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |  |  |
Share-based compensation, number of shares authorized (in shares) | 800,000 |  |  |  |  |  |  |
Payroll deduction discount | 10.00% |  |  |  |  |  |  |
Purchase price of common stock percent of the fair market value | 85.00% |  |  |  |  |  |  |
Common stock purchased (in shares) |  |  |  | 25,722 |  |  |  |
Proceeds from ESPP |  |  |  |  |  | $ 400 |  |
2003 Stock Incentive Plan |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |  |  |
Options outstanding (in shares) |  | 580,190 |  | 580,190 |  |  |  |
Weighted-average exercise price of stock options outstanding (in dollars per share) |  | $ 2.28 |  | $ 2.28 |  |  |  |
Stock Incentive Plan 2013 |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |  |  |
Share-based compensation, number of shares authorized (in shares) |  | 9,938,263 |  | 9,938,263 |  |  |  |
Potential annual increase in shares reserved for future issuance (in shares) |  | 1,960,168 |  | 1,960,168 |  |  |  |
Potential annual increase in shares reserved for future issuance as percentage of outstanding share |  |  |  | 4.00% |  |  |  |
Options outstanding (in shares) |  | 6,181,599 |  | 6,181,599 |  |  |  |
Weighted-average exercise price of stock options outstanding (in dollars per share) |  | $ 24.42 |  | $ 24.42 |  |  |  |
Research and Development |  |  |  |  |  |  |  |
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items] |  |  |  |  |  |  |  |
Stock-based compensation expense |  |  |  | $ 2,453 | 1,989 | 4,267 | $ 3,689 |
General and Administrative |  |  |  |  |  |  |  |
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items] |  |  |  |  |  |  |  |
Stock-based compensation expense |  |  |  | $ 2,431 | $ 2,174 | $ 4,416 | $ 3,906 |

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- Definition Represents the expense recognized during the period arising from equity-based compensation arrangements (for example, shares of stock, unit, stock options or other equity instruments) with employees, directors and certain consultants qualifying for treatment as employees. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5047-113901 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SAB Topic 14.F) -URI http://asc.fasb.org/extlink&oid=115993241&loc=d3e301413-122809 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (h)(1)(i) -URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5070-113901 + Details
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- Definition The cash inflow associated with the amount received from the stock plan during the period. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 14 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=109223946&loc=d3e3255-108585 + Details
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- Definition The aggregate amount of noncash, equity-based employee remuneration. This may include the value of stock or unit options, amortization of restricted stock or units, and adjustment for officers' compensation. As noncash, this element is an add back when calculating net cash generated by operating activities using the indirect method. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=109223946&loc=d3e3602-108585 + Details
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- Definition The maximum number of shares (or other type of equity) originally approved (usually by shareholders and board of directors), net of any subsequent amendments and adjustments, for awards under the equity-based compensation plan. As stock or unit options and equity instruments other than options are awarded to participants, the shares or units remain authorized and become reserved for issuance under outstanding awards (not necessarily vested). + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (a)(3) -URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5070-113901 + Details
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- Definition Number of options outstanding, including both vested and non-vested options. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5070-113901 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1)(i)-(ii) -URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5070-113901 + Details
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- Definition Weighted average price at which grantees can acquire the shares reserved for issuance under the stock option plan. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1)(i) -URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5070-113901 + Details
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