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v3.19.2

CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY - USD ($) $ in Thousands | Total | Common Stock | Additional Paid-In Capital | Accumulated Deficit | Accumulated Other Comprehensive Income (Loss)
--- | --- | --- | --- | --- | ---
Beginning balance (in shares) at Dec. 31, 2017 |  | 36,859,077 |  |  |
Beginning balance at Dec. 31, 2017 | $ 299,238 | $ 369 | $ 611,270 | $ (312,340) | $ (61)
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |
Share-based compensation | 3,386 |  | 3,386 |  |
Stock plan related activity | 629 | $ 1 | 628 |  |
Stock plan related activity (in shares) |  | 165,546 |  |  |
Unrealized gain on investments | 38 |  |  |  | 38
Net loss | (49,536) |  |  | (49,536) |
Ending balance (in shares) at Mar. 31, 2018 |  | 37,024,623 |  |  |
Ending balance at Mar. 31, 2018 | 247,276 | $ 370 | 615,284 | (368,355) | (23)
Beginning balance (in shares) at Dec. 31, 2017 |  | 36,859,077 |  |  |
Beginning balance at Dec. 31, 2017 | 299,238 | $ 369 | 611,270 | (312,340) | (61)
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |
Net loss | (92,780) |  |  |  |
Ending balance (in shares) at Jun. 30, 2018 |  | 42,229,011 |  |  |
Ending balance at Jun. 30, 2018 | 312,036 | $ 422 | 723,196 | (411,599) | 17
Beginning balance (in shares) at Mar. 31, 2018 |  | 37,024,623 |  |  |
Beginning balance at Mar. 31, 2018 | 247,276 | $ 370 | 615,284 | (368,355) | (23)
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |
Share-based compensation | 4,209 |  | 4,209 |  |
Issuance of common stock, net of offering costs (in shares) |  | 5,175,000 |  |  |
Issuance of common stock, net of offering costs | 103,259 | $ 52 | 103,207 |  |
Stock plan related activity | 496 |  | 496 |  |
Stock plan related activity (in shares) |  | 29,388 |  |  |
Unrealized gain on investments | 40 |  |  |  | 40
Net loss | (43,244) |  |  | (43,244) |
Ending balance (in shares) at Jun. 30, 2018 |  | 42,229,011 |  |  |
Ending balance at Jun. 30, 2018 | 312,036 | $ 422 | 723,196 | (411,599) | 17
Beginning balance (in shares) at Dec. 31, 2018 |  | 42,353,301 |  |  |
Beginning balance at Dec. 31, 2018 | 242,877 | $ 424 | 732,727 | (490,271) | (3)
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |
Share-based compensation | 3,750 |  | 3,750 |  |
Issuance of common stock, net of offering costs (in shares) |  | 6,325,000 |  |  |
Issuance of common stock, net of offering costs | 118,657 | $ 63 | 118,594 |  |
Stock plan related activity | 347 | $ 1 | 346 |  |
Stock plan related activity (in shares) |  | 126,707 |  |  |
Unrealized gain on investments | 3 |  |  |  | 3
Net loss | (45,017) |  |  | (45,017) |
Ending balance (in shares) at Mar. 31, 2019 |  | 48,805,008 |  |  |
Ending balance at Mar. 31, 2019 | 320,617 | $ 488 | 855,417 | (535,288) | 0
Beginning balance (in shares) at Dec. 31, 2018 |  | 42,353,301 |  |  |
Beginning balance at Dec. 31, 2018 | $ 242,877 | $ 424 | 732,727 | (490,271) | (3)
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |
Stock plan related activity (in shares) | 1,796,645 |  |  |  |
Net loss | $ (76,784) |  |  |  |
Ending balance (in shares) at Jun. 30, 2019 |  | 48,893,451 |  |  |
Ending balance at Jun. 30, 2019 | 294,451 | $ 489 | 860,983 | (567,055) | 34
Beginning balance (in shares) at Mar. 31, 2019 |  | 48,805,008 |  |  |
Beginning balance at Mar. 31, 2019 | 320,617 | $ 488 | 855,417 | (535,288) | 0
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |
Share-based compensation | 4,933 |  | 4,933 |  |
Stock plan related activity | 634 | $ 1 | 633 |  |
Stock plan related activity (in shares) |  | 88,443 |  |  |
Unrealized gain on investments | 34 |  |  |  | 34
Net loss | (31,767) |  |  | (31,767) |
Ending balance (in shares) at Jun. 30, 2019 |  | 48,893,451 |  |  |
Ending balance at Jun. 30, 2019 | $ 294,451 | $ 489 | $ 860,983 | $ (567,055) | $ 34

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