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CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($) $ in Thousands | 3 Months Ended | 6 Months Ended
--- | --- | ---
Jun. 30, 2019 | Jun. 30, 2018 | Jun. 30, 2019 | Jun. 30, 2018
Revenues: |  |  |  |
Revenues | $ 10,593 | $ 18,834 | $ 20,255 | $ 23,529
Costs and expenses: |  |  |  |
Research and development | 51,440 | 52,014 | 98,500 | 97,684
General and administrative | 12,122 | 11,134 | 22,341 | 20,369
Total costs and expenses | 63,562 | 63,148 | 120,841 | 118,053
Loss from operations | (52,969) | (44,314) | (100,586) | (94,524)
Other income | 21,202 | 1,070 | 23,802 | 1,744
Net loss | (31,767) | (43,244) | (76,784) | (92,780)
Other comprehensive income: |  |  |  |
Unrealized gain on investments | 34 | 40 | 37 | 79
Comprehensive loss | $ (31,733) | $ (43,204) | $ (76,747) | $ (92,701)
Basic and diluted net loss per common share (in usd per share) | $ (0.65) | $ (1.03) | $ (1.63) | $ (2.35)
Basic and diluted weighted average common shares outstanding (in shares) | 48,845,234 | 42,153,813 | 47,234,889 | 39,559,599
Revenue From Collaborative Agreements |  |  |  |
Revenues: |  |  |  |
Revenues | $ 9,987 | $ 18,552 | $ 19,484 | $ 23,053
Revenue From Government Agreements |  |  |  |
Revenues: |  |  |  |
Revenues | $ 606 | $ 282 | $ 771 | $ 476

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