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Collaboration and Other Agreements, I-Mab Biopharma (Details) - USD ($)
$ in Thousands
 3 Months Ended 12 Months Ended
Dec. 31, 2019
Sep. 30, 2019
Jun. 30, 2019
Mar. 31, 2019
Dec. 31, 2018
Sep. 30, 2018
Jun. 30, 2018
Mar. 31, 2018
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Collaboration and Other Agreements [Line Items]                      
Revenues $ 25,192 $ 18,741 $ 10,593 $ 9,662 $ 15,794 $ 20,798 $ 18,834 $ 4,695 $ 64,188 $ 60,121 $ 157,742
Deferred revenue         $ 40,722         $ 40,722 $ 27,318
I-Mab Biopharma Collaboration And License Agreement | I-Mab                      
Collaboration and Other Agreements [Line Items]                      
Non-refundable upfront payment                 15,000    
Potential development and regulatory milestone payments 135,000               135,000    
Estimated variable consideration                 1,000    
Revenues                 2,300    
Deferred revenue 13,500               13,500    
Deferred revenue, current 4,400               4,400    
Deferred revenue, noncurrent $ 9,100               $ 9,100