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Stock-Based Compensation - Stock Option Activity (Details) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended 12 Months Ended
Mar. 31, 2020
Mar. 31, 2019
Dec. 31, 2019
Shares      
Shares, Outstanding, Beginning Balance (in shares) 6,706,994    
Shares, Granted (in shares) 1,403,627    
Shares, Exercised (in shares) (172,387)    
Shares, Forfeited or expired (in shares) (293,295)    
Shares, Outstanding, Ending Balance (in shares) 7,644,939   6,706,994
Shares, Exercisable (in shares) 4,358,640    
Shares, Vested and expected to vest (in shares) 7,306,954    
Weighted- Average Exercise Price      
Weighted- Average Exercise Price, Outstanding, Beginning Balance (in dollars per share) $ 22.33    
Weighted- Average Exercise Price, Granted (in dollars per share) 11.49    
Weighted- Average Exercise Price, Exercised (in dollars per share) 0.94    
Weighted- Average Exercise Price, Forfeited or expired (in dollars per share) (18.97)    
Weighted- Average Exercise Price, Outstanding, Ending Balance (in dollars per share) 20.95   $ 22.33
Weighted- Average Exercise Price, Exercisable (in dollars per share) 23.05    
Weighted- Average Exercise Price, Vested and expected to vest (in dollars per share) $ 21.04    
Share-based Compensation Arrangement by Share-based Payment Award, Options, Additional Disclosures [Abstract]      
Weighted- Average Remaining Contractual Term, Outstanding 7 years 1 month 6 days   6 years 10 months 24 days
Weighted- Average Remaining Contractual Term, Exercisable 5 years 7 months 6 days    
Weighted- Average Remaining Contractual Term, Vested and expected to vest 7 years    
Aggregate Intrinsic Value, Outstanding, Ending Balance $ 1,185    
Aggregate Intrinsic Value, Exercisable 1,184    
Aggregate Intrinsic Value, Vested and expected to vest $ 1,185    
Weighted-average grant-date fair value of options granted (in dollars per share) $ 7.12 $ 14.65  
Intrinsic value of options exercised $ 1,100 $ 1,600  
Cash received for options exercised 200 300  
Fair value of shares vested 3,700 $ 3,100  
Unrecognized compensation expense related to non-vested stock-options, net of related forfeiture estimates $ 33,000    
Unrecognized compensation expense recognition period 2 years 8 months 12 days