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CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY - USD ($)
$ in Thousands
Total
Common Stock
Additional Paid-In Capital
Accumulated Deficit
Accumulated Other Comprehensive Income
Beginning balance (in shares) at Dec. 31, 2018   42,353,301      
Beginning balance at Dec. 31, 2018 $ 242,877 $ 424 $ 732,727 $ (490,271) $ (3)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Share-based compensation 3,750   3,750    
Issuance of common stock, net of offering costs (in shares)   6,325,000      
Issuance of common stock, net of offering costs 118,657 $ 63 118,594    
Stock plan related activity (in shares)   126,707      
Stock plan related activity 347 $ 1 346    
Unrealized gain (loss) on investments 3       3
Net loss (45,017)     (45,017)  
Ending balance (in shares) at Mar. 31, 2019   48,805,008      
Ending balance at Mar. 31, 2019 320,617 $ 488 855,417 (535,288) 0
Beginning balance (in shares) at Dec. 31, 2019   48,958,763      
Beginning balance at Dec. 31, 2019 230,628 $ 490 872,204 (642,082) 16
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Share-based compensation $ 4,451   4,451    
Stock plan related activity (in shares) 1,403,627 172,387      
Stock plan related activity $ 162 $ 2 160    
Unrealized gain (loss) on investments 56       56
Net loss (44,724)     (44,724)  
Ending balance (in shares) at Mar. 31, 2020   49,131,150      
Ending balance at Mar. 31, 2020 $ 190,573 $ 492 $ 876,815 $ (686,806) $ 72