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Stock-Based Compensation - Stock Option Activity (Details) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended 6 Months Ended
Mar. 31, 2020
Jun. 30, 2020
Jun. 30, 2019
Shares      
Shares, Outstanding, Beginning Balance (in shares) 6,706,994 6,706,994  
Shares, Granted (in shares)   1,547,627  
Shares, Exercised (in shares)   (329,592)  
Shares, Forfeited or expired (in shares)   (650,489)  
Shares, Outstanding, Ending Balance (in shares)   7,274,540  
Shares, Exercisable (in shares)   4,134,978  
Shares, Vested and expected to vest (in shares)   6,954,436  
Weighted- Average Exercise Price      
Weighted- Average Exercise Price, Outstanding, Beginning Balance (in dollars per share) $ 22.33 $ 22.33  
Weighted- Average Exercise Price, Granted (in dollars per share)   12.67  
Weighted- Average Exercise Price, Exercised (in dollars per share)   7.31  
Weighted- Average Exercise Price, Forfeited or expired (in dollars per share)   (20.90)  
Weighted- Average Exercise Price, Outstanding, Ending Balance (in dollars per share)   21.07  
Weighted- Average Exercise Price, Exercisable (in dollars per share)   23.32  
Weighted- Average Exercise Price, Vested and expected to vest (in dollars per share)   $ 21.17  
Share-based Compensation Arrangement by Share-based Payment Award, Options, Additional Disclosures [Abstract]      
Weighted- Average Remaining Contractual Term, Outstanding 6 years 10 months 24 days 7 years 2 months 12 days  
Weighted- Average Remaining Contractual Term, Exercisable   5 years 10 months 24 days  
Weighted- Average Remaining Contractual Term, Vested and expected to vest   7 years 1 month 6 days  
Aggregate Intrinsic Value, Outstanding, Ending Balance   $ 54,434  
Aggregate Intrinsic Value, Exercisable   23,276  
Aggregate Intrinsic Value, Vested and expected to vest   $ 51,498  
Weighted-average grant-date fair value of options granted (in dollars per share)   $ 8.30 $ 14.38
Intrinsic value of options exercised   $ 2,600 $ 2,600
Cash received for options exercised   2,400 600
Fair value of shares vested   7,400 $ 6,500
Unrecognized compensation expense related to non-vested stock-options, net of related forfeiture estimates   $ 31,200  
Unrecognized compensation expense recognition period   2 years 4 months 24 days