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Collaboration and Other Agreements - Provention Bio, Inc. (Details)
 3 Months Ended 9 Months Ended
May 31, 2018
USD ($)
performance_obligation
$ / shares
shares
Sep. 30, 2020
USD ($)
Sep. 30, 2019
USD ($)
Sep. 30, 2018
USD ($)
Sep. 30, 2020
USD ($)
Sep. 30, 2019
USD ($)
Dec. 31, 2019
USD ($)
Collaboration And Other Agreements [Line Items]              
Revenues   $ 18,253,000 $ 18,741,000   $ 52,192,000 $ 38,996,000  
Fair Value   $ 79,022,000     $ 79,022,000   $ 89,284,000
Provention              
Collaboration And Other Agreements [Line Items]              
Number of performance obligations | performance_obligation 2            
Collaborative agreement transaction price $ 6,100,000            
Number of shares available under warrants (in shares) | shares 2,432,688            
License Agreement | Provention | Provention PRV-3279              
Collaboration And Other Agreements [Line Items]              
Warrant to purchase shares of common stock, exercise price (in dollars per share) | $ / shares $ 2.50            
Potential development and regulatory milestone payments under agreement $ 65,000,000.0            
Potential commercial milestone payments under agreement $ 225,000,000.0            
Asset Purchase Agreement | Provention | Provention PRV-031              
Collaboration And Other Agreements [Line Items]              
Warrant to purchase shares of common stock, exercise price (in dollars per share) | $ / shares $ 2.50            
Potential development and regulatory milestone payments under agreement $ 170,000,000.0            
Potential commercial milestone payments under agreement 225,000,000.0            
Potential milestone payments to third parties $ 1,300,000            
Revenues From License Agreements | Provention              
Collaboration And Other Agreements [Line Items]              
Revenues       $ 6,100,000