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Collaboration and Other Agreements - Zai Lab (Details) - USD ($)
$ in Thousands
 1 Months Ended 12 Months Ended
Nov. 30, 2018
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Feb. 29, 2020
Collaboration and Other Agreements [Line Items]          
Revenues   $ 104,883 $ 64,188 $ 60,121  
Zai Lab Agreement | Zai Lab          
Collaboration and Other Agreements [Line Items]          
Non-refundable upfront payment $ 25,000        
Tax withholding $ 2,500        
Potential development and regulatory milestone payments   140,000      
Revenues   8,600 16,100 $ 1,300  
Deferred revenue   5,000      
Entitled milestone payments         $ 3,600
Zai Lab Agreement, Margetuximab | Zai Lab | Maximum          
Collaboration and Other Agreements [Line Items]          
Potential proceeds from royalties percent 20.00%        
Zai Lab Agreement, TRIDENT molecule | Zai Lab          
Collaboration and Other Agreements [Line Items]          
Potential proceeds from royalties percent 10.00%        
Zai Lab Clinical Supply Agreements | Zai Lab          
Collaboration and Other Agreements [Line Items]          
Revenues   2,700 $ 2,200    
Zai Lab Collaboration And License Agreement | Zai Lab          
Collaboration and Other Agreements [Line Items]          
Non-refundable upfront payment, net of tax withholding $ 22,500        
Revenues   4,000      
Revenues, tax withholding   $ 400